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Karbinal ER

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Karbinal ER

Karbinal™ ER
(carbinoxamine maleate) Extended-Release Oral Suspension

DRUG DESCRIPTION

Each 5 mL of Karbinal ER Extended-release Oral Suspension contains carbinoxamine complexed with polistirex equivalent to 4 mg carbinoxamine maleate and the following inactive ingredients: citric acid anhydrous, strawberry-banana flavor, glycerin, high fructose corn syrup, methylparaben, modified food starch, polysorbate 80, polyvinyl acetate, povidone, propylparaben, purified water, sodium metabisulfite, sodium polystyrene sulfonate, sucrose, triacetin, and xanthan gum.

Carbinoxamine maleate is freely soluble in water. The chemical name is 2-[(4-chlorophenyl)-2- pyridinylmethoxy]-N, N-dimethylethanamine (Z)-2-butenedioate (1:1), which has the following structure:

Carbinoxamine maleate Structural Formula Illustration

C16H19ClN2O•C4H4O4       MW = 406.86

The drug-polistirex complex is formed with the active ingredient (carbinoxamine maleate, USP) and sodium polystyrene sulfonate, USP, which has the following structure:

sodium polystyrene sulfonate Structural Formula Illustration

Last reviewed on RxList: 4/15/2013
This monograph has been modified to include the generic and brand name in many instances.

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