"The U.S. Food and Drug Administration today approved Clinolipid (lipid injectable emulsion, USP) for intravenous feeding (parenteral nutrition) in adult patients, providing a source of calories and essential fatty acids for adult patients who are"...
Overdosage may result in electrolyte disturbances including hypokalemia, hypocalcemia, and hypomagnesemia. Biochemical disturbances resulting from overdosage may give rise to clinical signs and symptoms of hypokalemia, including: irritability, confusion, delayed thought processes, muscle weakness, hyporeflexia, which may progress to frank paralysis and/or apnea. Tetany may occur. Electrocardiographic changes may be consistent with hypokalemia or hypocalcemia; cardiac arrhythmias may occur. Appropriate measures should be taken to correct serum electrolytes (potassium, calcium, magnesium), and the resin should be removed from the alimentary tract by appropriate use of laxatives or enemas.
Kayexalate (sodium polystyrene) is contraindicated in the following conditions: patients with hypokalemia, patients with a history of hypersensitiviry to polystyrene sulfonate resins, obstructive bowel disease, neonates with reduced gut motiliry (postoperatively or drug induced) and oral administration in neonates (see PRECAUTIONS).
Last reviewed on RxList: 2/28/2011
This monograph has been modified to include the generic and brand name in many instances.
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