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KCL in D5NS

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KCL in D5NS

Potassium Chloride in 5% Dextrose and Sodium Chloride (potassium chloride in 5% dextrose and sodium chloride injection)
Injection, USP in Plastic Container
Viaflex® Plus Container

DRUG DESCRIPTION

Potassium Chloride in 5% Dextrose and Sodium Chloride (potassium chloride in 5% dextrose and sodium chloride injection) Injection, USP is a sterile, nonpyrogenic solution for fluid and electrolyte replenishment and caloric supply in a single dose container for intravenous administration. It contains no antimicrobial agents. Composition, osmolarity, pH, ionic concentration and caloric content are shown in Table 1.

Table 1

  Size (mL) Composition(g/L) *Osmolarity (mOsmol/L) (calc.) pH Ionic Concentration (mEq/L) Caloric Content (kcal/L)
**Dextrose Hydrous, USP Sodium Chloride, USP (NaCl) Potassium Chloride, USP (KCl) Sodium Potassium Chloride
Potassium Chloride in 5% Dextrose and 0.2% Sodium Chloride Injection, USP
mEq Potassium
10 mEq 1000 50 2 0.75 341 4.5
(3.5 to 6.5)
34 10 44 170
20 mEq 1000 50 2 1.5 361 4.5
34 20 54 170
10 mEq 500         (3.5 to 6.5)        
30 mEq 1000 50 2 2.24 381 4.5
(3.5 to 6.5)
34 30 64 170
40 mEq 1000 50 2 3 401 4.5
(3.5 to 6.5)
34 40 74 170
Potassium Chloride in 5% Dextrose and 0.33% Sodium Chloride Injection, USP
mEq Potassium
20 mEq 1000 50 3.3 1.5 405 4.5 56 20 76 170
10 mEq 500         (3.5 to 6.5)        
30 mEq 1000 50 3.3 2.24 425 4.5
(3.5 to 6.5)
56 30 86 170
40 mEq 1000 50 3.3 3 446 4.5
(3.5 to 6.5)
56 40 96 170
Potassium Chloride in 5% Dextrose and 0.45% Sodium Chloride Injection, USP
mEq Potassium
10 mEq 1000 50 4.5 0.75 426 4.5
(3.5 to 6.5)
77 10 87 170
20 mEq 1000 50 4.5 1.5 447 4.5 77 20 97 170
10 mEq 500         (3.5 to 6.5)        
30 mEq 1000 50 4.5 2.24 466 4.5
(3.5 to 6.5)
77 30 107 170
40 mEq 1000 50 4.5 3 487 4.5
(3.5 to 6.5)
77 40 117 170
Potassium Chloride in 5% Dextrose and 0.9% Sodium Chloride Injection, USP
mEq Potassium
20 mEq 1000 50 9 1.5 601 4.5
(3.5 to 6.5)
154 20 174 170
40 mEq 1000 50 9 3 641 4.5
(3.5 to 6.5)
154 40 194 170
*Normal physiologic osmolarity range is approximately 280 to 310 mOsmol/L.
Administration of substantially hypertonic solutions ( ≥ 600 mOsmol/L) may cause vein damage.

 Viaflex® Plus Container   Structural Formula Illustration

D-Glucose monohydrate

The Viaflex® Plus plastic container is fabricated from a specially formulated polyvinyl chloride (PL 146®Plastic). Viaflex®Plus on the container indicates the presence of a drug additive in a drug vehicle. The Viaflex®Plus plastic container system utilizes the same container as the Viaflex®plastic container system. The amount of water that can permeate from inside the container into the overwrap is insufficient to affect the solution significantly. Solutions in contact with the plastic container can leach out certain of its chemical components in very small amounts within the expiration period, e.g., di-2-ethylhexyl phthalate (DEHP), up to 5 parts per million. However, the safety of the plastic has been confirmed in tests in animals according to USP biological tests for plastic containers as well as by tissue culture toxicity studies.

Last reviewed on RxList: 12/29/2008
This monograph has been modified to include the generic and brand name in many instances.

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