Kenalog-40 Injection (Triamcinolone Acetonide Injectable Suspension) Drug Information: Description, User Reviews, Drug Side Effects, Interactions

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May 27, 2012

Kenalog-40

Hypercalcemia (Elevated Calcium Levels) »

Hypercalcemia Introduction

Calcium is a mineral that is important in the regulation and processes of many body functions including bone formation, hormone release, muscle contraction, and nerve and brain function. Hypercalcemia is the term that refers to elevated levels of calcium in the bloodstream.

Regulation of Calcium

Calcium levels are tightly regulated in the body. Calcium regulation is primarily controlled by parathyroid hormone (PTH), vitamin D, and calcitonin.

Parathyroid hormone is a hormone produced by the parathyroid glands, which are four small glands that surround the thyroid and are found in the anterior part of the lower neck.
Vitamin D is obtained through a process that begins with sun exposure to the skin, the process then continues in the liver and kidneys. Vitamin D can also be found in foods such as eggs and dairy products.
Calcitonin is produc...

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Kenalog-40 Injection User Reviews >>

Kenalog-40 Injection

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KENALOG®-40 INJECTION
(triamcinolone acetonide) Injectable Suspension, USP

NOT FOR USE IN NEONATES
CONTAINS BENZYL ALCOHOL

For Intramuscular or Intra-articular Use Only

NOT FOR INTRAVENOUS, INTRADERMAL, INTRAOCULAR, EPIDURAL, OR INTRATHECAL USE

DRUG DESCRIPTION

Kenalog®-40 Injection (triamcinolone acetonide injectable suspension, USP) is a synthetic glucocorticoid corticosteroid with anti-inflammatory action. THIS FORMULATION IS SUITABLE FOR INTRAMUSCULAR AND INTRAARTICULAR USE ONLY. THIS FORMULATION IS NOT FOR INTRADERMAL INJECTION.

Each mL of the sterile aqueous suspension provides 40 mg triamcinolone acetonide, with sodium chloride for isotonicity, 0.99% (w/v) benzyl alcohol as a preservative, 0.75% carboxymethylcellulose sodium, and 0.04% polysorbate 80. Sodium hydroxide or hydrochloric acid may be present to adjust pH to 5.0 to 7.5. At the time of manufacture, the air in the container is replaced by nitrogen.

The chemical name for triamcinolone acetonide is 9-Fluoro-11β,16α,17,21- tetrahydroxypregna-1,4-diene-3,20-dione cyclic 16,17-acetal with acetone. Its structural formula is:

Kenalog®-40 (triamcinolone acetonide) Structural Formula Illustration

Triamcinolone acetonide occurs as a white to cream-colored, crystalline powder having not more than a slight odor and is practically insoluble in water and very soluble in alcohol.

What are the precautions when taking triamcinolone acetonide injectable suspension (Kenalog-40 Injection)?

Before using this medication, tell your doctor or pharmacist if you are allergic to it; or to other corticosteroids (e.g., methylprednisolone); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: untreated active fungal infections.

If your have a certain bleeding disorder (idiopathic thrombocytopenic purpura), consult your doctor before injecting this medication into a muscle.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: bleeding problems,...

Read All Potential Precautions of Kenalog-40 Injection »

Last reviewed on RxList: 6/24/2011
This monograph has been modified to include the generic and brand name in many instances.