"An estimated half a million epinephrine autoinjectors are coming off the market. The US Food and Drug Administration (FDA) is advising patients to call their doctor for an alternative, but some say there won't be enough supply to meet the demand."...
(triamcinolone acetonide) Injectable Suspension, USP
NOT FOR INTRAVENOUS, INTRADERMAL, INTRAOCULAR, EPIDURAL, OR INTRATHECAL USE
Kenalog®-40 Injection (triamcinolone acetonide injectable suspension, USP) is a synthetic glucocorticoid corticosteroid with anti-inflammatory action. THIS FORMULATION IS SUITABLE FOR INTRAMUSCULAR AND INTRAARTICULAR USE ONLY. THIS FORMULATION IS NOT FOR INTRADERMAL INJECTION.
Each mL of the sterile aqueous suspension provides 40 mg triamcinolone acetonide, with 0.65% sodium chloride for isotonicity, 0.99% (w/v) benzyl alcohol as a preservative, 0.75% carboxymethylcellulose sodium, and 0.04% polysorbate 80. Sodium hydroxide or hydrochloric acid may be present to adjust pH to 5.0 to 7.5. At the time of manufacture, the air in the container is replaced by nitrogen.
The chemical name for triamcinolone acetonide is 9-Fluoro-11β,16α,17,21- tetrahydroxypregna-1,4-diene-3,20-dione cyclic 16,17-acetal with acetone. Its structural formula is:
Triamcinolone acetonide occurs as a white to cream-colored, crystalline powder having not more than a slight odor and is practically insoluble in water and very soluble in alcohol.
What are the possible side effects of triamcinolone injection?
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have a serious side effect such as:
- fast, slow, or uneven heart rate;
- feeling short of breath, even with mild exertion;
- swelling, rapid weight gain;
- dangerously high blood pressure (severe headache, buzzing in your ears, anxiety, confusion, chest pain);
- problems with your vision;
- eye swelling, redness, discomfort, or drainage (may be...
What are the precautions when taking triamcinolone acetonide injectable suspension (Kenalog-40 Injection)?
Before using this medication, tell your doctor or pharmacist if you are allergic to it; or to other corticosteroids (e.g., methylprednisolone); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: untreated active fungal infections.
If your have a certain bleeding disorder (idiopathic thrombocytopenic purpura), consult your doctor before injecting this medication into a muscle.
Before using this medication, tell your doctor or pharmacist your medical history, especially of: bleeding problems,...
Last reviewed on RxList: 11/12/2015
This monograph has been modified to include the generic and brand name in many instances.
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