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Ketamine Hydrochloride

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Ketamine Hydrochloride

Ketamine Hydrochloride

Ketamine Hydrochloride Side Effects Center

Medical Editor: John P. Cunha, DO, FACOEP

Ketamine Hydrochloride (ketamine hcl) Injection (Brand Names: Ketalar) is used as a general anesthetic to prevent pain and discomfort during medical tests or procedures, or minor surgery. It is an anesthetic. This medication is available in generic form. Common side effects include dream-like feeling, double vision, jerky muscle movements, dizziness, drowsiness, nausea, vomiting, loss of appetite, or sleep problems (insomnia).

This medication is administered under a physician's supervision. The initial dose of ketamine administered intravenously (IV) ranges from 1 mg/kg to 4.5 mg/kg. The average amount required to produce five to ten minutes of surgical anesthesia is 2 mg/kg. The initial dose of ketamine administered intramuscularly (IM) ranges from 6.5 to 13 mg/kg. A dose of 10 mg/kg usually produces 12 to 25 minutes of surgical anesthesia. Ketamine hydrochloride may interact with barbiturates or narcotics. Tell your doctor all medications you use. Ketamine hydrochloride is not recommended for use during pregnancy. It is unknown if this medication passes into breast milk. Consult your doctor before breast-feeding. You may have withdrawal symptoms if you suddenly stop taking Ketamine hydrochloride.

Our Ketamine Hydrochloride (ketamine hcl) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is Patient Information in Detail?

Easy-to-read and understand detailed drug information and pill images for the patient or caregiver from Cerner Multum.

Ketamine Hydrochloride in Detail - Patient Information: Side Effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Tell your caregivers at once if you have any of these serious side effects within 24 hours after you receive ketamine:

  • severe confusion;
  • hallucinations;
  • unusual thoughts; or
  • extreme fear.

Less serious side effects may include:

  • dream-like feeling;
  • double vision;
  • jerky muscle movements;
  • dizziness, drowsiness;
  • nausea, vomiting, loss of appetite; or
  • sleep problems (insomnia).

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

Read the entire detailed patient monograph for Ketamine Hydrochloride (Ketamine HCl) »

What is Prescribing information?

The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.

Ketamine Hydrochloride FDA Prescribing Information: Side Effects
(Adverse Reactions)

SIDE EFFECTS

Cardiovascular

Blood pressure and pulse rate are frequently elevated following administration of ketamine alone. However hypotension and bradycardia have been observed. Arrhythmia has also occurred.

Respiration

Although respiration is frequently stimulated, severe depression of respiration or apnea may occur following rapid intravenous administration of high doses of ketamine. Laryngospasms and other forms of airway obstruction have occurred during ketamine anesthesia.

Eye

Diplopia and nystagmus have been noted following ketamine administration. It also may cause a slight elevation in intraocular pressure meas- urement.

Psychological

(See Special Note)

Neurological

In some patients, enhanced skeletal muscle tone may be manifested by tonic and clonic movements sometimes resembling seizures (see DOSAGE AND ADMINISTRATION).

Gastrointestinal

Anorexia, nausea and vomiting have been observed; however, this is not usually severe and allows the great majority of patients to take liquids by mouth shortly after regaining consciousness (see DOSAGE AND ADMINISTRATION).

General

Anaphylaxis. Local pain and exanthema at the injection site have infrequently been reported. Transient erythema and/or morbilliform rash have also been reported.

Drug Abuse And Dependence

Ketamine has been reported being used as a drug of abuse. Reports suggest that ketamine produces a variety of symptoms including, but not limited to, flashbacks, hallucinations, dysphoria, anxiety, insomnia, or disorientaion. Ketamine dependence and tolerance may develop in individuals with a history of drug abuse or dependence. Therefore, ketamine should be prescribed and administered with caution.

Read the entire FDA prescribing information for Ketamine Hydrochloride (Ketamine HCl) »

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Report Problems to the Food and Drug Administration

 

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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