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In the event of acute overdosage, the stomach should be emptied by gastric lavage. The patient should be carefully monitored (e.g., ECG, electrolytes) and given symptomatic and supportive treatment. Adequate hydration should be maintained. The effectiveness of hemodialysis in an overdose situation with KETEK (telithromycin) is unknown.


KETEK (telithromycin) is contraindicated in patients with myasthenia gravis. Exacerbations of myasthenia gravis have been reported in patients and sometimes occurred within a few hours of the first dose of telithromycin. Reports have included fatal and life-threatening acute respiratory failure with a rapid onset and progression.

KETEK (telithromycin) is contraindicated in patients with previous history of hepatitis and/or jaundice associated with the use of KETEK (telithromycin) tablets, or any macrolide antibiotic.

KETEK (telithromycin) is contraindicated in patients with a history of hypersensitivity to telithromycin and/or any components of KETEK (telithromycin) tablets, or any macrolide antibiotic.

Concomitant administration of KETEK (telithromycin) with cisapride or pimozide is contraindicated. (See CLINICAL PHARMACOLOGY, Drug-drug Interactions and PRECAUTIONS.)

Concomitant administration of KETEK (telithromycin) and colchicine is contraindicated in patients with renal or hepatic impairment. (See WARNINGS, DRUG INTERACTIONS and PRECAUTIONS: DRUG INTERACTIONS.)

Last reviewed on RxList: 1/27/2011
This monograph has been modified to include the generic and brand name in many instances.


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