May 29, 2016
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Ketek

"Middle East Respiratory Syndrome Coronavirus (MERS-CoV), formerly called "novel coronavirus (nCoV)," was identified in 2012 in Saudi Arabia. Most people who got infected with MERS-CoV developed severe acute respiratory illness with symptoms of fe"...

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Ketek




Overdosage
Contraindications

OVERDOSE

In the event of acute overdosage, the stomach should be emptied by gastric lavage. The patient should be carefully monitored (e.g., ECG, electrolytes) and given symptomatic and supportive treatment. Adequate hydration should be maintained. The effectiveness of hemodialysis in an overdose situation with KETEK is unknown.

CONTRAINDICATIONS

Myasthenia Gravis

KETEK is contraindicated in patients with myasthenia gravis. Exacerbations of myasthenia gravis have been reported in patients and sometimes occurred within a few hours of the first dose of KETEK. Reports have included fatal and life-threatening acute respiratory failure with a rapid onset and progression.

Hepatitis

KETEK is contraindicated in patients with previous history of hepatitis and/or jaundice associated with the use of KETEK tablets, or any macrolide antibacterial. [see WARNINGS AND PRECAUTIONS]

Hypersensitivity

KETEK is contraindicated in patients with a history of hypersensitivity to telithromycin, any components of KETEK tablets, or any macrolide antibacterial.[see DESCRIPTION]

Cisapride/Pimozide

Concomitant administration of KETEK with cisapride or pimozide is contraindicated because coadministration can lead to life-threatening QT prolongation. [see WARNINGS AND PRECAUTIONS; DRUG INTERACTIONS]

Colchicine

Concomitant administration of KETEK and colchicine is contraindicated in patients with renal or hepatic impairment due to increased plasma concentration of colchicine leading to life-threatening colchicine toxicity. [see WARNINGS AND PRECAUTIONS; DRUG INTERACTIONS]

This monograph has been modified to include the generic and brand name in many instances.

Last reviewed on RxList: 5/19/2016

Overdosage
Contraindications

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