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Kidney Failure

Does kidney failure cause pain?

Kidney failure in itself does not cause pain. However, the consequences of kidney failure may cause pain and discomfort in different parts of the body.

Amyloid proteins

Normal functioning kidneys filter amyloid (a protein) from the blood stream. In kidney failure amyloid proteins in the blood rise, and can separate and clump together forming amyloid deposits into a variety of tissue and organs, including joints and tendons. This can result in symptoms of:

  • joint stiffness,
  • pain, and
  • swelling.

Procedure related pain

Underlying chronic disease pain

  • Pain is often a consequence of the underlying chronic disease that led to kidney failure, for example:
  • People with poorly controlled diabetes may develop diabetic neuropathy pain.
  • People who have peripheral vascular disease also may have pain in their extremities, and may develop claudication (leg pain that occurs with walking).
Reviewed on 10/27/2016

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