July 30, 2015
Recommended Topic Related To:

Kinevac

"The U.S. Food and Drug Administration today approved Dotarem (gadoterate meglumine) for use in magnetic resonance imaging (MRI) of the brain, spine and associated tissues of patients ages 2 years and older.

Dotarem is a gadolinium-based"...

Kinevac

KINEVAC®
(sincalide) for Injection




DRUG DESCRIPTION

Kinevac (Sincalide for Injection) is a cholecystopancreatic-gastrointestinal hormone peptide for parenteral administration. The agent is a synthetically-prepared C-terminal octapeptide of cholecystokinin. Each vial of sincalide provides a sterile nonpyrogenic lyophillized white powder consisting of 5 mcg sincalide with 170 mg mannitol, 30 mg arginine hydrochloride, 15 mg lysine hydrochloride, 9 mg potassium phosphate dibasic, 4 mg methionine, 2 mg pentetic acid, 0.04 mg sodium metabisulfite, and 0.005 mcg polysorbate 20. The pH is adjusted to 6.0 - 8.0 with hydrochloric acid and/or sodium hydroxide prior to lyophilization. Sincalide is designated chemically as L-α-aspartyl-O-sulfo-L-tyrosyl-L-methionylglycyl-L-tryptophyl-L-methionyl-L-α-aspartyl-L-phenylalaninamide. Graphic formula:

Kinevac (Sincalide) Structural Formula Illustration

What are the possible side effects of sincalide (Kinevac)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Less serious side effects are more likely, such as:

  • stomach pain or discomfort;
  • nausea, vomiting, diarrhea;
  • headache;
  • feeling light-headed or short of breath;
  • sweating, flushing (warmth, redness, or tingly feeling);
  • sneezing; or
  • mild skin rash.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about...

Read All Potential Side Effects and See Pictures of Kinevac »

Last reviewed on RxList: 3/3/2015
This monograph has been modified to include the generic and brand name in many instances.

Report Problems to the Food and Drug Administration

 

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


Women's Health

Find out what women really need.