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Kinevac

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Kinevac

KINEVAC®
(sincalide) for Injection




DRUG DESCRIPTION

Kinevac (Sincalide for Injection) is a cholecystopancreatic-gastrointestinal hormone peptide for parenteral administration. The agent is a synthetically-prepared C-terminal octapeptide of cholecystokinin. Each vial of sincalide provides a sterile nonpyrogenic lyophillized white powder consisting of 5 mcg sincalide with 170 mg mannitol, 30 mg arginine hydrochloride, 15 mg lysine hydrochloride, 9 mg potassium phosphate dibasic, 4 mg methionine, 2 mg pentetic acid, 0.04 mg sodium metabisulfite, and 0.005 mcg polysorbate 20. The pH is adjusted to 6.0 - 8.0 with hydrochloric acid and/or sodium hydroxide prior to lyophilization. Sincalide is designated chemically as L-α-aspartyl-O-sulfo-L-tyrosyl-L-methionylglycyl-L-tryptophyl-L-methionyl-L-α-aspartyl-L-phenylalaninamide. Graphic formula:

Kinevac (Sincalide) Structural Formula Illustration

What are the possible side effects of sincalide (Kinevac)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Less serious side effects are more likely, such as:

  • stomach pain or discomfort;
  • nausea, vomiting, diarrhea;
  • headache;
  • feeling light-headed or short of breath;
  • sweating, flushing (warmth, redness, or tingly feeling);
  • sneezing; or
  • mild skin rash.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about...

Read All Potential Side Effects and See Pictures of Kinevac »

Last reviewed on RxList: 3/3/2015
This monograph has been modified to include the generic and brand name in many instances.

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Report Problems to the Food and Drug Administration

 

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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