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Kinevac (Sincalide for Injection) is a cholecystopancreatic-gastrointestinal hormone peptide for parenteral administration. The agent is a synthetically-prepared C-terminal octapeptide of cholecystokinin. Each via] of sincalide provides a sterile nonpyrogenic lyophilized white powder consisting of 5 mcg sincalide with 45 mg sodium chloride to provide tonicity; sodium hydroxide or hydrochloric acid may have been added prior to lyophilization for pH adjustment (5.5 to 6.5). At the time of manufacture, the air in the vial is replaced with nitrogen. Sincalide is designated chemically as L-aspartyl-L-tyrosyl-L-methionylglycyl-L-tryptophyl-L-methionyl-L-aspartylphenyK-alaninamide hydrogen sulfate (ester). Graphic formula:

Last reviewed on RxList: 10/8/2008
This monograph has been modified to include the generic and brand name in many instances.