June 29, 2016
Recommended Topic Related To:

Kinevac

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Kinevac




Overdosage
Contraindications

OVERDOSE

Although no overdosage reports have been received, gastrointestinal symptoms (abdominal cramps, nausea, vomiting and diarrhea) would be expected. Hypotension with dizziness or fainting might also occur. Overdosage symptoms should be treated symptomatically and should be of short duration. Starting with single bolus i.v. injection comparable to the human dose of 0.4 mg/kg, sincalide caused hypotension and bradycardia in dogs. Higher doses injected once or repeatedly in dogs caused syncope and ECG changes in addition. These effects were attributed to sincalide-induced vagal stimulation in that all were prevented by pretreatment with atropine or bilateral vagotomy.

CONTRAINDICATIONS

The preparation is contraindicated in patients hypersensitive to sincalide and in patients with intestinal obstruction.

This monograph has been modified to include the generic and brand name in many instances.

Last reviewed on RxList: 3/3/2015

Overdosage
Contraindications

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You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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