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Kinevac Side Effects Center
Medical Editor: Melissa Conrad Stöppler, MD
Kinevac (sincalide for Injection) is a cholecystopancreatic-gastrointestinal hormone peptide administered by intravenous injection in certain medical tests. It is primarily used to assist in diagnosing disorders of the gallbladder and pancreas. Common side effects include abdominal discomfort or pain, and nausea.
For prompt contraction of the gallbladder, a dose of 0.02 mcg of Kinevac (sincalide) per kg (1.4 mcg/70 kg) is injected intravenously over a 30- to 60-second interval; if satisfactory contraction of the gallbladder does not occur in 15 minutes, a second dose, 0.04 mcg Kinevac (sincalide) per kg, may be administered. Because of Kinevac's (sincalide) effect on smooth muscle, pregnant patients should be advised that spontaneous abortion or premature induction of labor may occur. Talk to your doctor about Kinevac if you are breastfeeding before receiving treatment with this drug.
Our (sincalide for Injection) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What is Patient Information in Detail?
Easy-to-read and understand detailed drug information and pill images for the patient or caregiver from Cerner Multum.
Kinevac in Detail - Patient Information: Side Effects
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Less serious side effects are more likely, such as:
- stomach pain or discomfort;
- nausea, vomiting, diarrhea;
- feeling light-headed or short of breath;
- sweating, flushing (warmth, redness, or tingly feeling);
- sneezing; or
- mild skin rash.
Read the entire detailed patient monograph for Kinevac (Sincalide)
What is Prescribing information?
The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.
Kinevac FDA Prescribing Information: Side Effects
Reactions to sincalide are generally mild and of short duration. The most frequent adverse reactions were abdominal discomfort or pain, and nausea; rapid intravenous injection of 0.04 mcg sincalide per kg expectably causes transient abdominal cramping. These phenomena are usually manifestations of the physiologic action of the drug, including delayed gastric emptying and increased intestinal motility. These reactions occurred in approximately 20 percent of patients; they are not to be construed as necessarily indicating an abnormality of the billiary tract unless there is other clinical or radiologic evidence of disease.
The incidence of other adverse reactions, including vomiting, flushing, sweating, rash, hypotension, hypertension, shortness of breath, urge to defecate, headache, diarrhea, sneezing, and numbness was less than 1 percent; dizziness was reported in approximately 2 percent of patients. These manifestations are usually lessened by slower injection rate.
Read the entire FDA prescribing information for Kinevac (Sincalide)
Additional Kinevac Information
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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