"Analysis of three biomarkers in the urine of kidney transplant recipients can diagnose — and even predict — transplant rejection, according to results from a clinical trial sponsored by the National Institute of Allergy and Infect"...
(sodium polystyrene sulfonate) USP Cation-Exchange Resin
Kionex® brand of sodium polystyrene sulfonate is a benzene, diethenyl- polymer with ethenylbenzene, sulfonated, sodium salt and has the following structural formula:
The drug is a cream to light brown finely ground, powdered form of sodium polystyrene sulfonate, a cation-exchange resin prepared in the sodium phase with an in vitro exchange capacity of approximately 3.1 mEq (in vivo approximately 1 mEq) of potassium per gram. The sodium content is approximately 100 mg (4.1 mEq) per gram of the drug. It can be administered orally or in an enema.
What are the possible side effects of sodium polystyrene sulfonate (Kalexate, Kayexalate, Kionex)?
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Tell your caregivers right away if you have any of these serious side effects:
- pain or fluttering in your chest;
- uneven heartbeats;
- feeling irritable or confused;
- increased thirst or urination;
- severe muscle weakness;
- inability to move your muscles;
- black, bloody, or tarry stools;
- pain in your lower stomach or rectum;...
What are the precautions when taking sodium polystyrene sulfonate (Kionex)?
Before using sodium polystyrene sulfonate, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
This medication contains a large amount of salt (sodium). Do not use salt substitutes that contain potassium without asking your doctor first. If you have any of these conditions, follow your doctor's instructions for limiting the amount of sodium in your diet: kidney problems, heart failure, high blood pressure, swelling hands/ankles/feet.
Before using this medication, tell your doctor or pharmacist your medical history, especially of: stomach/intestine/bowel problems (such as inflammatory bowel...
Last reviewed on RxList: 10/8/2007
This monograph has been modified to include the generic and brand name in many instances.
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