Kionex (Sodium Polystyrene Sulfonate) Drug Information: Description, User Reviews, Drug Side Effects, Interactions

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February 9, 2012

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Kionex

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Kionex®
(sodium polystyrene sulfonate) USP Cation-Exchange Resin

DRUG DESCRIPTION

Kionex® brand of sodium polystyrene sulfonate is a benzene, diethenyl- polymer with ethenylbenzene, sulfonated, sodium salt and has the following structural formula:

Kionex (Sodium Polystyrene Sulfonate) structural formula illustration

The drug is a cream to light brown finely ground, powdered form of sodium polystyrene sulfonate, a cation-exchange resin prepared in the sodium phase with an in vitro exchange capacity of approximately 3.1 mEq (in vivo approximately 1 mEq) of potassium per gram. The sodium content is approximately 100 mg (4.1 mEq) per gram of the drug. It can be administered orally or in an enema.

What are the possible side effects of sodium polystyrene sulfonate (Kayexalate, Kionex)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Tell your caregivers right away if you have any of these serious side effects:

pain or fluttering in your chest;
uneven heartbeats;
feeling irritable or confused;
increased thirst or urination;
severe muscle weakness;
inability to move your muscles;
black, bloody, or...

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What are the precautions when taking sodium polystyrene sulfonate (Kionex)?

Before using sodium polystyrene sulfonate, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: blockage of the stomach/intestines, low level of potassium in the blood.

This medication contains a large amount of salt (sodium). If you have any of these conditions listed below, follow your doctor's instructions for limiting the amount of sodium in your diet. Do not use salt substitutes that contain potassium without asking your doctor...

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Last reviewed on RxList: 10/8/2007
This monograph has been modified to include the generic and brand name in many instances.