"The U.S. Food and Drug Administration today notified Ranbaxy Laboratories, Ltd., that it is prohibited from manufacturing and distributing active pharmaceutical ingredients (APIs) from its facility in Toansa, India, for FDA-regulated drug product"...
Konyne Side Effects Center
Medical Editor: John P. Cunha, DO, FACOEP
Konyne (factor IX complex) 80 is a clotting factor used to treat or prevent bleeding in people with hemophilia B. Some forms of factor IX complex may also be used to treat or prevent bleeding in people with factor VII deficiency or inhibitors to factor VIII. This medication is available in generic form. Common side effects include pain at injection site, chills, tingling, flushing, headache, nausea, or vomiting.
The dose of Konyne 80 required for normalizing hemostasis will depend upon the patient and upon the circumstances. Konyne may interact with other drugs that affect bleeding or blood-clotting processes. Tell your doctor all medications and supplements you use. During pregnancy, Konyne should be used only if prescribed. It is unknown if this drug passes into breast milk. Consult your doctor before breastfeeding.
Our Konyne (factor IX complex) 80 Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What is Patient Information in Detail?
Easy-to-read and understand detailed drug information and pill images for the patient or caregiver from Cerner Multum.
Konyne in Detail - Patient Information: Side Effects
Factor IX complex is made from human plasma (part of the blood) and may contain infectious agents (e.g., viruses) that can cause disease. Although factor IX complex is screened, tested, and treated to reduce the possibility that it carries an infectious agent, it can still potentially transmit disease. Discuss with your doctor the risks and benefits of using factor IX complex.
Some viruses, such as parovovirus B19 and hepatitis A, may be more difficult to identify or remove from factor IX complex. Parovovirus B19 may more seriously affect pregnant women and those with poor immune systems. Symptoms of parovovirus B19 infection include fever, chills, runny nose, and drowsiness followed about 2 weeks later by a rash and joint pain. Symptoms of hepatitis A may include several days to weeks of poor appetite, tiredness, and low-grade fever followed by nausea, vomiting, and pain in the belly. Dark-colored urine and yellowing of the skin or whites of the eyes may also occur. Contact your doctor if you develop any of these symptoms after treatment with factor IX complex.
If you experience any of the following serious side effects, contact your healthcare provider immediately or seek emergency medical attention:
- an allergic reaction (shortness of breath; wheezing; tightness of the chest; closing of the throat; hives; swelling of the lips, face, or tongue; hives or rash; dizziness or fainting); or
- nausea or vomiting;
- increased heart rate;
- decreased blood pressure (may result in dizziness or fainting);
- difficulty breathing, chest pain, or cough; or
- pain, redness, or swelling at the injection site.
Other, less serious side effects may be more likely to occur. Continue to use factor IX complex and talk to your doctor if you experience
- headache; or
Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.
Read the entire detailed patient monograph for Konyne (Factor IX Complex) »
What is Patient Information Overview?
A concise overview of the drug for the patient or caregiver from First DataBank.
Konyne Overview - Patient Information: Side Effects
Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
Tell your doctor right away if you have any serious side effects, including: swelling at injection site, fast heartbeat, shortness of breath, change in the amount of urine, swelling of the ankles/feet, pain/redness/swelling of arms or legs, new or increased bleeding/bruising.
Get medical help right away if any of these rare but very serious side effects occur: chest pain, trouble breathing, bluish fingers.
This medication is made from human blood. Even though donors are carefully screened and this medication goes through a special manufacturing process, there is a very small chance that you may get infections from the medication (e.g., viral infections such as hepatitis). Tell your doctor immediately if you develop any signs of hepatitis/another infection, including fever, persistent sore throat, unusual tiredness, persistent nausea/vomiting, yellowing eyes/skin, dark urine.
A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
In the US -
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
Read the entire patient information overview for Konyne (Factor IX Complex)»
What is Prescribing information?
The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.
Konyne FDA Prescribing Information: Side Effects
Additional Konyne Information
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
Find out what women really need.