Korlym

Korlym Patient Information including How Should I Take

What should I discuss with my healthcare provider before taking Korlym (Korlym)?

You should not take Korlym if you are allergic to mifepristone, or if you have:

  • unusual or unexplained vaginal bleeding;
  • endometrial hyperplasia or a certain type of uterine cancer;
  • if you are pregnant; or
  • if you take steroid medications because of a serious illness or condition (such as an organ transplant).

The following drugs should not be used while you are taking Korlym:

  • alfentanil (Alfenta);
  • cyclosporine (Gengraf, Neoral, Sandimmune);
  • digoxin (digitalis, Lanoxin, Lanoxicaps);
  • ergotamine (Ergomar, Cafergot) or dihydroergotamine (D.H.E. 45, Migranal Nasal Spray);
  • fentanyl (Abstral, Actiq, Fentora, Duragesic, Lazanda, Onsolis);
  • pimozide (Orap);
  • quinidine (Quin-G);
  • lovastatin (Mevacor, Altoprev, Advicor) or simvastatin (Zocor, Simcor, Vytorin, Juvisync); or

To make sure you can safely take Korlym, tell your doctor if you have any of these other conditions:

  • liver or kidney disease;

The following drugs should not be used while you are taking Korlym:

  • sirolimus (Rapamune) or tacrolimus (Prograf).

To make sure you can safely take Korlym, tell your doctor if you have any of these other conditions:

  • heart disease, heart failure, coronary artery disease;
  • high blood pressure;
  • endometriosis;
  • a problem with your thyroid or adrenal glands; or
  • an autoimmune disorder such as rheumatoid arthritis, systemic lupus erythematosus (SLE), or psoriasis.

FDA pregnancy category X. Korlym can harm an unborn baby or cause a miscarriage. Do not use if you are pregnant. Stop taking Korlym and tell your doctor right away if you become pregnant during treatment.

You will need to have a negative pregnancy test before you start taking Korlym, or if you restart the medication after not taking it for longer than 2 weeks.

Korlym can make birth control pills less effective. Use a non-hormone method of birth control (such as a condom with spermicide or diaphragm with spermicide) while you are using this medication and for at least 1 month after your treatment ends.

It is not known whether Korlym passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

How should I take Korlym (Korlym)?

Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.

Korlym is usually taken once per day with a meal. Follow your doctor's instructions.

While using Korlym, you may need blood tests at your doctor's office. Visit your doctor regularly.

Store at room temperature away from moisture and heat.

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