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Korlym Patient Information Including Side Effects

Brand Names: Korlym

Generic Name: mifepristone (Korlym) (Pronunciation: MIF e PRIS tone)

What is mifepristone (Korlym) (Korlym)?

This medication guide provides information about the Korlym brand of mifepristone. Mifeprex is another brand of mifepristone that is not covered in this medication guide.

Korlym blocks the actions of a hormone called cortisol, which can reduce certain side effects caused by excess cortisol in the body.

Korlym is used to treat high blood sugar (hyperglycemia) in adults with Cushing's syndrome who also have type 2 diabetes or glucose intolerance.

This medication should not be used to treat type 2 diabetes that is not related to Cushing's syndrome.

Korlym may also be used for purposes not listed in this medication guide.

What are the possible side effects of Korlym (Korlym)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop using Korlym and call your doctor at once if you have a serious side effect such as:

  • nausea, weakness, tired feeling, feeling like you might pass out;
  • fever, chills, cough with yellow or green mucus;
  • stabbing chest pain, wheezing, feeling short of breath;
  • swelling in your hands or feet;
  • unusual or irregular vaginal bleeding;
  • low blood sugar (headache, hunger, weakness, sweating, confusion, irritability, dizziness, fast heart rate, or feeling jittery); or
  • low potassium (confusion, uneven heart rate, extreme thirst, increased urination, leg discomfort, muscle weakness or limp feeling).

Less serious side effects may include:

  • stomach pain, mild nausea or vomiting;
  • diarrhea or constipation;
  • dry mouth;
  • stuffy nose, sinus congestion, sore throat;
  • headache, dizziness;
  • muscle pain or weakness, joint pain, back pain;
  • decreased appetite; or
  • sleep problems (insomnia).

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Read the Korlym (mifepristone) Side Effects Center for a complete guide to possible side effects

What is the most important information I should know about Korlym (Korlym)?

This medication guide provides information about the Korlym brand of mifepristone. Mifeprex is another brand of mifepristone that is not covered in this medication guide.

Korlym can harm an unborn baby or cause a miscarriage. Do not use if you are pregnant. You will need to have a negative pregnancy test before you start taking Korlym, or if you restart the medication after not taking it for longer than 2 weeks.

You should not take Korlym if you are allergic to mifepristone, or if you have unexplained vaginal bleeding, endometrial hyperplasia or a certain type of uterine cancer, if you are pregnant, or if you take steroid medications because of a serious illness or condition (such as an organ transplant).

Before you take Korlym, tell your doctor if you have liver or kidney disease, heart disease, heart failure, coronary artery disease, high blood pressure, endometriosis, a problem with your thyroid or adrenal glands, or an autoimmune disorder.

There are many other drugs that should not be used together with Korlym. Tell your doctor about all other medicines you use.

Side Effects Centers

Report Problems to the Food and Drug Administration


You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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