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Kuvan

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Kuvan

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OVERDOSE

In the only reported overdosage with Kuvan (saproterin dihydrochloride tablets) , a patient participating in a 26-week study received a single dose of 4,500 mg (36 mg/kg) instead of 2,600 mg (20 mg/kg) in Week 16. The patient reported mild headache and mild dizziness immediately after taking the dose; both symptoms resolved within 1 hour with no treatment intervention. Results from liver function laboratory tests obtained immediately following the event were within normal limits. The patient suspended therapy for 24 hours and then restarted Kuvan (saproterin dihydrochloride tablets) with no reports of abnormal signs or symptoms.

CONTRAINDICATIONS

None.

Last reviewed on RxList: 1/3/2008
This monograph has been modified to include the generic and brand name in many instances.

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Cholesterol Management

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