February 23, 2017
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Lactated Ringers

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Lactated Ringer's

DEXTROSE IN LACTATED RINGERS
(dextrose, sodium chloride, sodium lactate, potassium chloride, and calcium chloride) injection, solution

5% Dextrose in Lactated Ringer's Injection

DRUG DESCRIPTION

Each 100 mL of 5% Dextrose in Lactated Ringer's Injection contains:

Hydrous Dextrose USP 5 g; Sodium Chloride USP 0.6 g
Sodium Lactate 0.31 g; Potassium Chloride USP 0.03 g
Calcium Chloride Dihydrate USP 0.02 g
Water for Injection USP qs

pH adjusted with Hydrochloric Acid NF
pH: 4.6 (4.0-6.0)
Calories per liter: 170
Calculated Osmolarity: 530 mOsmol/liter, hypertonicConcentration of Electrolytes (mEq/liter): Sodium 130 Potassium 4

Calcium 3 Chloride 112 Lactate (CH3CH(OH)COO-) 28

5% Dextrose in Lactated Ringer's Injection is sterile, nonpyrogenic and contains no bacteriostatic or antimicrobial agents. This product is intended for intravenous administration.

The formulas of the active ingredients are:

Ingredients Molecular Formula Molecular Weight
Sodium Chloride USP NaCl 58.44
Sodium Lactate CH3CH(OH)COONa 112.06
Potassium Chloride USP KCl 74.55
Calcium Chloride Dihydrate USP CaCl2•2H2O 147.02
Hydrous Dextrose USP 5% Dextrose in Lactated Ringer's Injection  Structural Formula Illustration 198.17

The EXCEL® Container is Latex-free, PVC-free, and DEHP-free.

The plastic container is made from a multilayered film specifically developed for parenteral drugs. It contains no plasticizers and exhibits virtually no leachables. The solution contact layer is a rubberized copolymer of ethylene and propylene. The container is nontoxic and biologically inert. The containersolution unit is a closed system and is not dependent upon entry of external air during administration. The container is overwrapped to provide protection from the physical environment and to provide an additional moisture barrier when necessary.

Addition of medication should be accomplished using complete aseptic technique.

The closure system has two ports; the one for the administration set has a tamper evident plastic protector and the other is a medication addition site. Refer to the Directions for Use of the container.

Last reviewed on RxList: 10/3/2016
This monograph has been modified to include the generic and brand name in many instances.

Report Problems to the Food and Drug Administration

 

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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