Lamisil Oral Granules (Terbinafine Hydrochloride) Drug Information: Description, User Reviews, Drug Side Effects, Interactions

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February 10, 2012

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Lamisil Oral Granules

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Lamisil® Oral Granules
(terbinafine hydrochloride)

DRUG DESCRIPTION

Lamisil (terbinafine hydrochloride) Oral Granules 125 mg and 187.5 mg contain the synthetic allylamine antifungal compound, terbinafine hydrochloride.

Chemically, terbinafine hydrochloride is (E)-N-(6,6-dimethyl-2-hepten-4-ynyl)-N-methyl-1-naphthalenemethanamine hydrochloride. It has the empirical formula C₂₁H₂₆ClN with a molecular weight of 327.90, and the following structural formula:

Lamisil (terbinafine hydrochloride) structural formula illustration

Terbinafine hydrochloride is a white to off-white fine crystalline powder. It is freely soluble in methanol and methylene chloride, soluble in ethanol, and slightly soluble in water.

Each packet of Lamisil Oral Granules contains:

Active Ingredients: terbinafine hydrochloride (equivalent to 125 mg or 187.5 mg terbinafine base)

Inactive Ingredients: basic butylated methacrylate copolymer, colloidal silicon dioxide NF, dibutyl sebacate NF, hypromellose USP, magnesium stearate NF, microcrystalline cellulose NF, nitrogen NF (filling gas), polyethylene glycol NF, sodium lauryl sulfate NF, and sodium starch glycolate NF.

What are the possible side effects of terbinafine (Lamisil)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Some people taking terbinafine have developed severe liver damage leading to liver transplant or death. It is not clear whether terbinafine actually caused the liver damage in these patients. In most cases, the patient had a serious medical condition before taking terbinafine.

Call your doctor at once if you have symptoms of liver damage, such as nausea, stomach...

Read All Potential Side Effects and See Pictures of Lamisil Oral Granules »

What are the precautions when taking terbinafine hydrochloride (Lamisil Oral Granules)?

Before taking terbinafine, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: liver disease.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: kidney disease, immune system problems, lupus.

Limit alcoholic beverages. Daily use of alcohol may increase your chance for serious side effects.

During pregnancy, this medication should be used only when clearly needed. Discuss the risks and...

Read All Potential Precautions of Lamisil Oral Granules »

Last reviewed on RxList: 10/18/2007
This monograph has been modified to include the generic and brand name in many instances.