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In this Article

• What is digoxin (Lanoxin)?
• What are the possible side effects of digoxin (Lanoxin)?
• What is the most important information I should know about digoxin (Lanoxin)?
• What should I discuss with my healthcare provider before taking digoxin (Lanoxin)?
• How should I take digoxin (Lanoxin)?
• What happens if I miss a dose (Lanoxin)?
• What happens if I overdose (Lanoxin)?
• What should I avoid while taking digoxin (Lanoxin)?
• What other drugs will affect digoxin (Lanoxin)?
• Where can I get more information?

What happens if I miss a dose (Lanoxin)?

Take the missed dose as soon as you remember. If your next dose is less than 12 hours away, wait until then to take the medicine and skip the missed dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose (Lanoxin)?

Seek emergency medical attention if you think you have used too much of this medicine.

Overdose symptoms may include nausea, vomiting, diarrhea, loss of appetite, blurred vision, seeing halos around lights or objects, severe skin rash, fast/slow or uneven heartbeats, and feeling like you might pass out.

What should I avoid while taking digoxin (Lanoxin)?

Avoid becoming overheated or dehydrated during exercise, in hot weather, or by not drinking enough fluids. Digoxin overdose can occur more easily if you are dehydrated.

What other drugs will affect digoxin (Lanoxin)?

Many drugs can interact with digoxin. Below is just a partial list. Tell your doctor if you are using:

• an antacid, or Kaopectate;
• alprazolam (Xanax);
• cancer medications;
• clonidine (Catapres);
• supplements or medications that contain calcium;
• a diuretic (water pill), such as spironolactone (Aldactone, Aldactazide);
• amphotericin B (Fungizone, AmBisome, Abelcet);
• cholestyramine (Questran, Prevalite);
• epinephrine (EpiPen);
• guanabenz (Wytensin) or guanfacine (Tenex);
• indomethacin (Indocin);
• isoproterenol (Isuprel);
• itraconazole (Sporanox);
• levothyroxine (Synthroid, Levothroid, and others);
• methyldopa (Aldomet);
• metoclopramide (Reglan);
• neomycin (Mycifradin, Neo-Fradin, Neo-Tab);
• rifampin (Rifadin, Rifater, Rifamate);
• sulfasalazine (Azulfidine); or
• an antibiotic such as erythromycin (E.E.S., EryPed, Ery-Tab, Erythrocin), clarithromycin (Biaxin), or tetracycline (Brodspec, Panmycin, Sumycin, Tetracap);
• a beta-blocker such as carvedilol (Coreg), metoprolol (Lopressor, Toprol), and others;
• a calcium channel blocker such as amlodipine (Norvasc), diltiazem (Tiazac, Cartia, Cardizem), felodipine (Plendil), nisoldipine (Sular), verapamil (Calan, Covera, Isoptin, Verelan), and others;
• decongestant cold or allergy medicine, or nasal sprays such as Afrin, Duramist, Neo-Synephrine, Tysine Nasal, and others;
• a heart rhythm medication such as amiodarone (Cordarone, Pacerone), propafenone (Rythmol), or quinidine (Quinaglute, Quinidex, Quin-Release); or
• steroids such as prednisone, fluticasone (Advair), mometasone (Asmanex, Nasonex), dexamethasone (Decadron, Hexadrol) and others.

This list is not complete and there are many other medicines that can interact with digoxin. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor. Keep a list with you of all the medicines you use and show this list to any doctor or other healthcare provider who treats you.

Where can I get more information?

Your pharmacist can provide more information about digoxin.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

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