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An excess of insulin relative to food intake, energy expenditure, or both may lead to severe and sometimes long-term and life-threatening hypoglycemia. Mild episodes of hypoglycemia can usually be treated with oral carbohydrates. Adjustments in drug dosage, meal patterns, or exercise may be needed.
More severe episodes with coma, seizure, or neurologic impairment may be treated with intramuscular/subcutaneous glucagon or concentrated intravenous glucose. After apparent clinical recovery from hypoglycemia, continued observation and additional carbohydrate intake may be necessary to avoid reoccurrence of hypoglycemia.
LANTUS (insulin glargine [rdna origin] injection) is contraindicated in patients hypersensitive to insulin glargine or the excipients.
Last reviewed on RxList: 1/14/2008
This monograph has been modified to include the generic and brand name in many instances.
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