DRUG INTERACTIONS: Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with them first.

This drug should not be used with the following medications because very serious interactions may occur: artemether-lumefantrine, chloroquine, halofantrine, ketoconazole, quinidine, quinine, ziprasidone.

Do not take halofantrine or ketoconazole for 15 weeks after your last dose of mefloquine.

Tell your doctor of all prescription and nonprescription drugs you may use, especially of: beta-blockers (e.g., atenolol, propranolol), live bacterial vaccines, drugs for seizures (e.g., carbamazepine, phenytoin, valproic acid), drugs affecting liver enzymes that remove mefloquine from your body (such as rifamycins - including rifabutin and rifampin, and azole antifungals - including itraconazole and ketoconazole).

This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.

OVERDOSE: If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly. Symptoms of overdose may include vomiting and diarrhea.

NOTES: Important to wear protective clothing, insect repellent, and use bednets when trying to prevent malaria.

Periodic eye examinations and laboratory tests (e.g., liver function tests) should be performed to monitor your progress or check for side effects. Consult your doctor or pharmacist for more details.

MISSED DOSE: If you miss a dose, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.

STORAGE: Store at room temperature at 77 degrees F (25 degrees C) away from sunlight and moisture. Brief storage between 59-86 degrees F (15-30 degrees C) is permitted. Do not store in bathroom. Keep all medicines away from children and pets.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details about how to safely discard your product.

Information last revised October 2010. Copyright(c) 2010 First Databank, Inc.