"The U.S. Food and Drug Administration today approved Ragwitek, the first allergen extract administered under the tongue (sublingually) to treat short ragweed pollen induced allergic rhinitis (hay fever), with or without conjunctivitis (eye inflam"...
(alcaftadine) Ophthalmic Solution
LASTACAFT™ (alcaftadine ophthalmic solution) is a sterile, topically administered H1 receptor antagonist containing alcaftadine for ophthalmic use.
Alcaftadine is a white to yellow powder with an empirical formula of C19H21N3O and a molecular weight of 307.39.
Active: alcaftadine 0.25% (2.5 mg/mL) Preservative: benzalkonium chloride 0.005%
Inactives: edetate disodium, monobasic sodium phosphate, purified water, sodium chloride, sodium hydroxide and/or hydrochloric acid (to adjust pH)
Chemical Name: 6,11-dihydro-11-(1-methyl-4-piperidinylidene)-5#-imidazo[2,1-b]  benzazepine-3-carboxaldehyde
The drug product has a pH of approximately 7 and an osmolality of approximately 290 mOsm/kg.
What are the possible side effects of alcaftadine ophthalmic (Lastacaft)?
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Stop using alcaftadine ophthalmic and call your doctor at once if you have severe burning, stinging, or other irritation after using the eye drops.
Less serious side effects may include:
- mild burnng, stinging, or irritation;
- eye redness or itching;
- runny or stuffy nose, sore throat, flu symptoms; or
This is not a complete list of side effects and...
What are the precautions when taking alcaftadine ophthalmic solution (Lastacaft)?
Before using alcaftadine, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Before using this medication, tell your doctor or pharmacist your medical history, especially of: contact lens use.
After you apply this drug, your vision may be temporarily unclear. Do not drive, use machinery, or do any activity that requires clear vision until you are sure you can perform such activities safely.
Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).
If you develop an eye infection...
Last reviewed on RxList: 8/20/2010
This monograph has been modified to include the generic and brand name in many instances.
Additional Lastacaft Information
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