"LONDON (Reuters) - AstraZeneca's high hopes for cancer immunotherapy were dented on Thursday as the recruitment of new patients with head and neck cancer into two clinical studies was put on hold, following instances of bleeding.
Lazanda Patient Information including How Should I Take
In this Article
- What is fentanyl nasal (Lazanda)?
- What are the possible side effects of fentanyl nasal (Lazanda)?
- What is the most important information I should know about fentanyl nasal (Lazanda)?
- What should I discuss with my healthcare provider before using fentanyl nasal (Lazanda)?
- How should I use fentanyl nasal (Lazanda)?
- What happens if I miss a dose (Lazanda)?
- What happens if I overdose (Lazanda)?
- What should I avoid while taking fentanyl nasal (Lazanda)?
- What other drugs will affect fentanyl nasal (Lazanda)?
- Where can I get more information?
What should I discuss with my healthcare provider before using fentanyl nasal (Lazanda)?
Do not use fentanyl nasal unless you are already being treated with a similar opioid pain medicine and your body is tolerant to it. Talk with your doctor if you are not sure you are opioid-tolerant.
Do not use fentanyl nasal if you have used an MAO inhibitor such as furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam, Zelapar), or tranylcypromine (Parnate) in the last 14 days.
Tell your doctor if there are children living in the home where you will store this medicine. Keep out of the reach of children. The amount of fentanyl in Lazanda can be fatal to a child.
To make sure you can safely use fentanyl nasal, tell your doctor if you have any of these other conditions:
- a breathing disorder such as wheezing, asthma, or chronic obstructive pulmonary disease (COPD);
- seizures, epilepsy, or a history of head injury or brain tumor;
- low blood pressure, slow heartbeats or other heart rhythm disorder;
- mental illness such as depression, schizophrenia, or hallucinations;
- liver or kidney disease;
- any type of debilitating condition; or
- a history of drug or alcohol addiction.
Fentanyl may be habit-forming and should be used only by the person it was prescribed for. Never share fentanyl with another person, especially someone with a history of drug abuse or addiction. Keep the medication in a place where others cannot get to it.
FDA pregnancy category C. It is not known whether fentanyl will harm an unborn baby. Fentanyl may cause breathing problems, seizure, or addiction and withdrawal symptoms in a newborn if the mother takes the medication during pregnancy. Tell your doctor if you are pregnant or plan to become pregnant while using fentanyl nasal.
Fentanyl may also cause drowsiness, breathing problems, or addiction and withdrawal symptoms in a nursing infant. Do not breast-feed while you are taking fentanyl nasal.
Do not give this medication to anyone under 18 years old.
How should I use fentanyl nasal (Lazanda)?
Do not use Lazanda to replace any other form of fentanyl, such as Abstral, Actiq, Fentora, Onsolis, Duragesic, or generic brands of fentanyl (injection, skin patch, dissolving film, or "lollipop" device).
Use exactly as prescribed. Never use fentanyl nasal in larger amounts, or for longer than recommended by your doctor. Keep using your around-the-clock narcotic pain medicine but never use Lazanda together with a second form of fentanyl.
This medication comes with patient instructions for safe use, and directions for priming and disposal of the nasal spray. Ask your doctor or pharmacist if you have any questions.
If you switch to Lazanda from another form of fentanyl, you will not use the same dose. You must start with the lowest dose (100 micrograms).
The usual starting dose of fentanyl nasal is 1 single spray into 1 nostril. Your doctor may change your dose to make sure you get the best results. Follow dosing instructions very carefully. Do not use more than one dose for each episode of breakthrough cancer pain.
Call your doctor if you still have pain within 30 minutes after using the nasal spray. Do not use the nasal spray more than 4 times in 24 hours. You must wait at least 2 hours after your last dose of fentanyl nasal before you can treat a new pain episode.
Do not treat more than 4 pain episodes per day with fentanyl nasal. Call your doctor if you have breakthrough pain more than 4 times in one day.
Do not stop using Lazanda or your other narcotic pain medicine without your doctor's advice. Ask your doctor how to avoid withdrawal symptoms when you stop using pain medication.
Keep out of the reach of children. The amount of fentanyl in each bottle of Lazanda can be fatal to a child.
Do not use a bottle of Lazanda that has not been used for 5 days or longer. Once you have primed a spray bottle, throw it away after 14 days, even if there is still medicine left in it.
Store at room temperature, away from heat and moisture. Keep the bottle tightly closed and stored in the child-resistant container when not in use.
Keep track of the amount of medicine used from each carton. Fentanyl is a drug of abuse and you should be aware if anyone is using your medicine improperly or without a prescription.
Additional Lazanda Information
- Lazanda Drug Interactions Center: fentanyl citrate nasl
- Lazanda Side Effects Center
- Lazanda FDA Approved Prescribing Information including Dosage
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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