Lemon Balm

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Are there any interactions with medications?



Sedative medications (CNS depressants)
Interaction Rating: Moderate Be cautious with this combination.
Talk with your health provider.

Lemon balm might cause sleepiness and drowsiness. Medications that cause sleepiness are called sedatives. Taking lemon balm along with sedative medications might cause too much sleepiness.

Some sedative medications include clonazepam (Klonopin), lorazepam (Ativan), phenobarbital (Donnatal), zolpidem (Ambien), and others.

Dosing considerations for Lemon Balm.

The following doses have been studied in scientific research:

BY MOUTH:
  • For mild to moderate Alzheimer's disease: 60 drops per day of a standardized lemon balm extract, prepared 1:1 in 45% alcohol.
  • For improving sleep in healthy adults: a specific combination product providing 80 mg of lemon balm leaf extract and 160 mg of valerian root extract (Euvegal forte, Schwabe Pharmaceuticals) 3 times daily for up to 30 days has been used. This same combination product, given once or twice daily, has been used for improving sleep in children.
  • For upset stomach (dyspepsia): a specific combination product containing lemon balm (Iberogast, Medical Futures, Inc) and several other herbs has been used in a dose of 1 mL three times daily over a period of 4 weeks. The combination includes lemon balm plus peppermint leaf, German chamomile, caraway, licorice, clown's mustard plant, celandine, angelica, and milk thistle.
  • For colic in breast-fed infants: a specific multi-ingredient product containing 164 mg of fennel, 97 mg of lemon balm, and 178 mg of German chamomile (ColiMil) twice daily for a week.
APPLIED TO THE SKIN:
  • For cold sores (herpes labialis): the cream or ointment containing 1% of a 70:1 freeze-dried water-soluble extract is usually applied two to four times daily from first sign of symptoms to a few days after the cold sores have healed.

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You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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