font size

Leprosy (cont.)

Medical Author:
Medical Editor:

How is leprosy transmitted?

Researchers suggest that M. leprae are spread person to person by nasal secretions or droplets. However, the disease is not highly contagious like the flu. They speculate that infected droplets reach other peoples' nasal passages and begin the infection there. Some investigators suggest the infected droplets can infect others by entering breaks in the skin. M. leprae apparently cannot infect intact skin. Rarely, humans get leprosy from the few animal species mentioned above. Occurrence in animals makes it difficult to eradicate leprosy from endemic sources. Routes of transmission are still being researched for leprosy. Recent genetic studies have demonstrated that several genes (about seven) are associated with an increased susceptibility to leprosy; some researchers now conclude that susceptibility to leprosy may be partially inheritable.

How is leprosy diagnosed?

The majority of cases of leprosy are diagnosed by clinical findings, especially since most current cases are diagnosed in areas that have limited or no laboratory equipment available. Hypopigmented patches of skin or reddish skin patches with loss of sensation, thickened peripheral nerves, or both clinical findings together often comprise the clinical diagnosis. Skin smears or biopsy material that show acid-fast bacilli with the Ziehl-Neelsen stain or the Fite stain (biopsy) can diagnose multibacillary leprosy, or if bacteria are absent, diagnose paucibacillary leprosy. Other tests can be done, but most of these are done by specialized labs and may help a clinician to place the patient in the more detailed Ridley-Jopling classification and are not routinely done (lepromin test, phenolic glycolipid-1 test, PCR, lymphocyte migration inhibition test or LMIT). Other tests such as CBC test, liver function tests, creatinine test, or a nerve biopsy may be done to help determine if other organ systems have been affected.


Patient Comments

Viewers share their comments

Leprosy - Symptoms Question: What were the symptoms of leprosy in you or someone you know?
Leprosy - Risk Factors Question: Have you ever been at risk for leprosy, either through travel or work? Please share your story.
Leprosy - Treatment Question: If you know or have helped someone with leprosy, what was the treatment for the disease?
Source: MedicineNet.com
http://www.medicinenet.com/leprosy/article.htm

Women's Health

Find out what women really need.

Leprosy Related Articles
advertisement
advertisement
Use Pill Finder Find it Now See Interactions

Pill Identifier on RxList

  • quick, easy,
    pill identification

Find a Local Pharmacy

  • including 24 hour, pharmacies

Interaction Checker

  • Check potential drug interactions
Search the Medical Dictionary for Health Definitions & Medical Abbreviations