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Statins (How They Work, Side Effects and Interactions) »
Statins (or HMG-CoA reductase inhibitors) are a class of drugs that reduce cholesterol in individuals who have dyslipidemia (abnormal fats in the blood) and thus are at risk for cardiovascular disease. Dyslipidemia may involve an elevation of total cholesterol, a reduction of low density lipoprotein (LDL) cholesterol and/or triglycerides, or a reduction of high density lipoprotein (HDL) cholesterol in blood. Statins work by blocking the enzyme in the liver that is responsible for making cholesterol. This enzyme is called hydroxy-methylglutaryl-coenzyme A reductase (HMG-CoA reductase).
Cholesterol is described as a soft wax-like fatty substance that is found in the blood stream and in cells. It is important to note that cholesterol is a naturally existing substance in all individuals from birth and its presence is actually necessary for promoting an overall healthy body. About 75% of cholesterol is produced by the liver and oth...
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Medical Editor: John P. Cunha, DO, FACOEP
Lescol (fluvastatin sodium) reduces low-density lipoprotein (LDL) cholesterol and total cholesterol in the blood, and is used to help prevent heart disease and hardening of the arteries, conditions that can lead to heart attack, stroke, and vascular disease. It is a cholesterol-lowering medication that blocks the production of cholesterol (a type of fat) in the body. Common side effects include stomach upset. Less frequent side effects include muscle pain/tenderness/weakness (especially with fever or unusual tiredness), or change in the amount of urine.
Dose range of Lescol is 20 mg to 80 mg/ day. Lescol may interact with stomach acid reducers, cholestyramine, danazol, diclofenac, glyburide, nefazodone, niacin, phenytoin, rifampin, gemfibrozil or fenofibrate, drugs that weaken your immune system such as cancer medicine or steroids, cyclosporine, tacrolimus, and others; amiodarone, diltiazem, or verapamil, antibiotics, antifungals, blood thinners, or HIV /AIDS medicine. Tell your doctor all medications you area taking. Lescol must not be used during pregnancy. It can cause birth defects. This medication passes into breast milk and may have undesirable effects on a nursing infant. Breast-feeding while using this drug is not recommended.
Our Lescol (fluvastatin sodium) Drug Center provides a comprehensive view of available drug information as well as related drugs, user reviews, supplements, and diseases and conditions articles.
What is Prescribing information?
The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.
Therapy with lipid-altering agents should be only one component of multiple risk factor intervention in individuals at significantly increased risk for atherosclerotic vascular disease due to hypercholesterolemia. Drug therapy is indicated as an adjunct to diet when the response to a diet restricted in saturated fat and cholesterol and other non-pharmacologic measures alone has been inadequate.
LESCOL and LESCOL XL are indicated
Read the complete drug monograph for Lescol »
Drug Description - Indications & Dosage - Side Effects & Drug Interactions - Warnings & Precautions - Contraindications - Medication Guide and More
What is Patient information?
Easy-to-read and understand detailed drug information and pill images for the patient or caregiver from Cerner Multum.
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop using fluvastatin and call your doctor at once if you have any of these serious side effects:
Less serious side effects may include:
This ...
Read the complete patient information for Lescol »
Possible Side Effects - Images - What Is - How Should I Take It - What If I Miss a Dose - What Should I Avoid and More
What is Consumer information?
A concise overview of the drug for the patient or caregiver from First DataBank.
In addition to eating a proper diet (such as a low-cholesterol/low-fat diet), other lifestyle changes that may help this medication work better include exercis...
Read the complete consumer information for Lescol »
Warnings - Uses - How to Use - Side Effects - Precautions - Drug Interactions and More
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
Tips to keep it under control.