"The largest study to date to focus on patients with colorectal cancer (CRC) with deficient DNA mismatch repair (dMMR) has found that adjuvant therapy with fluoropyrimidine combined with oxaliplatin (Eloxatin, Sanofi-Aventis), but not fluor"...
Leucovorin Side Effects Center
Medical Editor: John P. Cunha, DO, FACOEP
Leucovorin Calcium is a form of folic acid used to reduce the side effects of large doses or accidental overdose of medications that can reduce the effects of folic acid in the body. These medications include methotrexate, pyrimethamine, trimethoprim, and others. Leucovorin Calcium is available in generic form. Many people using Leucovorin Calcium do not have serious side effects. Infrequent side effects of Leucovorin Calcium include facial flushing, nausea, and vomiting. Seek immediate medical attention if you notice symptoms of a serious allergic reaction, including rash, itching or swelling (especially of the face/tongue/throat), severe dizziness, hives, or trouble breathing.
Dosage of Leucovorin Calcium is based on the patient's medical condition and response to treatment. Doses above 25 milligrams are not recommended. Leucovorin Calcium may interact with fluorouracil, phenytoin, fosphenytoin, ethotoin, phenobarbital, or primidone. Tell your doctor all medications and supplements you use. During pregnancy, Leucovorin Calcium should be used only when prescribed. It is unknown if this medication passes into breast milk. Consult your doctor before breastfeeding.
Our Leucovorin Calcium Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What is Patient Information in Detail?
Easy-to-read and understand detailed drug information and pill images for the patient or caregiver from Cerner Multum.
Leucovorin in Detail - Patient Information: Side Effects
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. You may report side effects to FDA at 1-800-FDA-1088.
Read the entire detailed patient monograph for Leucovorin (Leucovorin Calcium Tablets)
What is Patient Information Overview?
A concise overview of the drug for the patient or caregiver from First DataBank.
Leucovorin Overview - Patient Information: Side Effects
A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
In the US -
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
Read the entire patient information overview for Leucovorin (Leucovorin Calcium Tablets)
What is Prescribing information?
The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.
Leucovorin FDA Prescribing Information: Side Effects
Additional Leucovorin Calcium Information
Leucovorin Calcium - User Reviews
Leucovorin Calcium User Reviews
Now you can gain knowledge and insight about a drug treatment with Patient Discussions.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
Get the latest treatment options.