November 30, 2015
Recommended Topic Related To:


"The U.S. Food and Drug Administration today expanded the approved use of Imbruvica (ibrutinib) for chronic lymphocytic leukemia (CLL) patients who have received at least one previous therapy.

CLL is a rare blood and bone marrow disease"...




High doses of LEUSTATIN have been associated with: irreversible neurologic toxicity (paraparesis/quadriparesis), acute nephrotoxicity, and severe bone marrow suppression resulting in neutropenia, anemia and thrombocytopenia (see WARNINGS). There is no known specific antidote to overdosage. Treatment of overdosage consists of discontinuation of LEUSTATIN, careful observation and appropriate supportive measures. It is not known whether the drug can be removed from the circulation by dialysis or hemofiltration.


LEUSTATIN Injection is contraindicated in those patients who are hypersensitive to this drug or any of its components.

This monograph has been modified to include the generic and brand name in many instances.

Last reviewed on RxList: 8/9/2012


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