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See also How To Use section for drug-food interactions.

This drug should not be used with the following medications because very serious (possibly fatal) interactions may occur: nitrates (e.g., nitroglycerin, isosorbide), nitroprusside (or any "nitric oxide donor" drugs), recreational drugs called "poppers" containing amyl or butyl nitrite.

If you are currently using any of these medications, tell your doctor or pharmacist before starting vardenafil.

Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: alpha-blocker medication (e.g., doxazosin, prazosin, terazosin, or doses greater than 0.4 milligrams daily of tamsulosin), other medications for impotence, drugs that affect certain liver enzymes (CYP 3A4 substrates, inhibitors and inducers, e.g., cimetidine, rifamycins, St. John's wort, certain anti-seizure drugs), high blood pressure medicines.

If you are taking ritonavir or nelfinavir, do not take more than a 2.5 milligrams dose of vardenafil in a 72 hour period. If you are taking indinavir or high doses (400 milligrams daily) of either ketoconazole or itraconazole, do not take more than a 2.5 milligrams dose of vardenafil per day. If you are taking erythromycin or low doses (200 milligrams daily) of either ketoconazole or itraconazole, do not take more than 5 milligrams dose of vardenafil per day. For more details contact your doctor or pharmacist.

Many drugs besides vardenafil may affect the heart rhythm (QT prolongation), including dofetilide, pimozide, amiodarone, quinidine, sotalol, procainamide, macrolide antibiotics (such as erythromycin), sparfloxacin, among others. Therefore, before using vardenafil, report all medications you are currently using to your doctor or pharmacist.

Do not take this medication with any other product that contains vardenafil or other similar medications used to treat erectile dysfunction/pulmonary hypertension (e.g., sildenafil, tadalafil).

This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.

OVERDOSE: If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly. Symptoms of overdose may include back pain, muscle pain, abnormal vision.

NOTES: Do not share this medication with others, since they may have a problem that is not effectively treated by this drug, or they may have a condition that is complicated by this drug.

MISSED DOSE: Not applicable.

STORAGE: Store at room temperature at 77 degrees F (25 degrees C) away from light and moisture. Brief storage between 59-86 degrees F (15-30 degrees C) is permitted. Do not store in the bathroom. Keep all medicines away from children and pets.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details about how to safely discard your product.

Information last revised May 2010 Copyright(c) 2010 First DataBank, Inc.