Levo Dromoran (Levorphanol) Drug Information: Description, User Reviews, Drug Side Effects, Interactions

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February 10, 2012

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Levo Dromoran

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LEVO-DROMORAN
(levorphanol tartrate) Injection, Solution and Tablet

DRUG DESCRIPTION

Levo-Dromoran (levorphanol tartrate) is a potent opioid analgesic with empirical formula C₁₇H₂₃NO•C₄H₆O₆•2H₂O and molecular weight 443.5. Each mg of levorphanol tartrate is equivalent to 0.58 mg levorphanol base. Chemically levorphanol is levo-3-hydroxy-N-methylmorphinan. The USP nomenclature is 17-methylmorphinan 3-ol tartrate (1:1)(Salt) dihydrate. The material has 3 asymmetric carbon atoms. The chemical structure is:

Levo-Dromoran (levorphanol tartrate) Structural Formula Illustration

Levorphanol tartrate is a white crystalline powder, soluble in water and ether but insoluble in chloroform.

Each 1-mL ampul contains 2 mg levorphanol tartrate, 1.8 mg methyl paraben preservative, 0.2 mg propyl paraben preservative, sodium hydroxide to adjust pH to approximately 4.3 and Water for Injection.

Each milliliter in the 10 mL vials contains 2 mg levorphanol tartrate, 4.5 mg phenol preservative, sodium hydroxide to adjust pH to approximately 4.3 and Water for Injection.

Each tablet contains 2 mg levorphanol tartrate, lactose, corn starch, stearic acid and talc.

What are the possible side effects of levorphanol (Levo-Dromoran)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

shallow breathing, slow heartbeat;
seizure (convulsions);
cold, clammy skin;
confusion;
severe weakness or dizziness; or
feeling light-headed, fainting.

Less serious side effects are more likely to occur, such...

Read All Potential Side Effects and See Pictures of Levo Dromoran »

What are the precautions when taking levorphanol (Levo Dromoran)?

Before taking levorphanol, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: severe breathing problems (e.g., respiratory depression, severe or acute asthma), certain bowel diseases (e.g., paralytic ileus, toxic megacolon), intoxication with medications that slow the nervous system or your breathing (CNS/respiratory depressants such as alcohol or tranquilizers/sedatives).

Before using this medication, tell your doctor or pharmacist your...

Read All Potential Precautions of Levo Dromoran »

Last reviewed on RxList: 6/3/2009
This monograph has been modified to include the generic and brand name in many instances.