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Levo Dromoran

Last reviewed on RxList: 6/3/2009
Levo Dromoran Side Effects Center

Last reviewed on RxList 1/10/2016

Levo Dromoran (levorphanol tartrate) is a narcotic pain reliever, similar to morphine, used to treat moderate to severe pain. Common side effects of Levo Dromoran include nausea, vomiting, stomach pain, constipation, dizziness, lightheadedness, drowsiness, headache, fatigue, dry mouth, sweating, itching, double vision or other vision problems, and flushing (warmth, redness, or tingly feeling).

The recommended dosage of Levo Dromoran depends on whether it is in tablet or injectable form, as directed by your doctor. Levo Dromoran may interact with other medications for pain, MAO inhibitors, naltrexone, and cimetidine. Tell your doctor all medications you take. Do not drive, use machinery, or do any activity that requires alertness or clear vision while taking Levo Dromoran. Avoid alcoholic beverages. Levo Dromoran should be used during pregnancy only if clearly needed. Levo Dromoran passes into breast milk. Consult your doctor if you are breastfeeding.

Our Levo Dromoran (levorphanol tartrate) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Levo Dromoran Consumer Information

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have a serious side effect such as:

  • mood changes, confusion, unusual thoughts or behavior;
  • thoughts of suicide or hurting yourself;
  • feeling like you might pass out;
  • weak or shallow breathing;
  • cold, clammy skin;
  • blue lips or skin;
  • painful or difficult urination; or
  • slow heart rate, weak pulse, fainting, slow breathing (breathing may stop).

Less serious side effects are more likely to occur, such as:

  • dizziness, drowsiness;
  • nausea, vomiting, constipation, stomach pain;
  • dry mouth;
  • double vision;
  • itching, sweating; or
  • flushing (warmth, redness, or tingly feeling).

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Read the entire detailed patient monograph for Levo Dromoran (Levorphanol)

Levo Dromoran Professional Information

SIDE EFFECTS

In approximately 1400 patients treated with Levo-Dromoran (levorphanol) in controlled clinical trials, the type and incidence of side effects were those expected of an opioid analgesic, and no unforeseen or unusual toxicity was reported.

Drugs of this type are expected to produce a cluster of typical opioid effects in addition to analgesia, consisting of nausea, vomiting, altered mood and mentation, pruritus, flushing, difficulties in urination, constipation and biliary spasm. The frequency and intensity of these effects appears to be dose related. Although listed as adverse events these are expected pharmacologic actions of these drugs and should be interpreted as such by the clinician.

The following adverse events have been reported with the use of Levo-Dromoran (levorphanol) :

Body as a Whole: abdominal pain, dry mouth, sweating

Cardiovascular System: cardiac arrest, shock, hypotension, arrhythmias including bradycardia and tachycardia, palpitations, extrasystoles

Digestive System: nausea, vomiting, dyspepsia, biliary tract spasm

Nervous System: coma, suicide attempt, convulsions, depression, dizziness, confusion, lethargy, abnormal dreams, abnormal thinking, nervousness, drug withdrawal, hypokinesia, dyskinesia, hyperkinesia, CNS stimulation, personality disorder, amnesia, insomnia

Respiratory System: apnea, cyanosis, hypoventilation

Skin & Appendages: pruritus, urticaria, rash, injection site reaction

Special Senses: abnormal vision, pupillary disorder, diplopia

Urogenital System: kidney failure, urinary retention, difficulty urinating

Drug Abuse And Dependence

Warning: May be Habit Forming

Levo-Dromoran (levorphanol) is a Schedule II Controlled Substance. All drugs of this class (mu-opioids of the morphine type) are habit forming and should be stored, prescribed, used and disposed of accordingly. Psychological/physical dependence and tolerance may develop upon repeated administration of Levo-Dromoran (levorphanol) .

Discontinuation of Levo-Dromoran (levorphanol) after chronic use has been reported to result in withdrawal syndromes, and some reports of overuse and self-reported addiction have been received. Neither withdrawal nor withdrawal symptoms are usually expected in postoperative patients who used the drug for less than a week or in patients who are gradually tapered off the drug after longer use.

Read the entire FDA prescribing information for Levo Dromoran (Levorphanol)

Related Resources for Levo Dromoran

© Levo Dromoran Patient Information is supplied by Cerner Multum, Inc. and Levo Dromoran Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.

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