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Levothroid

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Levothroid

LEVOTHROID®
(levothyroxine sodium) Tablets, USP

Levothroid

DRUG DESCRIPTION

LEVOTHROID® (levothyroxine sodium) Tablets, USP contains synthetic crystalline L-3, 3', 5, 5'-tetraiodothyronine sodium salt [levothyroxine (T4) sodium]. Synthetic T4 is identical to that produced in the human thyroid gland. Levothyroxine (T4) sodium has an empirical formula of C15H10I4N NaO4 x H2O, molecular weight of 798. 86 g/mol (anhydrous), and structural formula as shown:

LEVOTHROID® (levothyroxine sodium) Structural Formula Illustration

Inactive Ingredients: Microcrystalline cellulose, calcium phosphate dibasic, povidone and magnesium stearate. The following are the coloring additives per tablet strength.

Strength (mcg) Color additive(s)
25 FD&C Yellow No.6 Aluminum Lake
50 None
75 FD&C Blue No.2 Aluminum Lake, FD&C Red No.40 Aluminum Lake
88 FD&C Yellow No.6 Aluminum Lake, FD&C Blue No.1 Aluminum Lake, D&C Yellow No.10 Aluminum Lake
100 FD&C Yellow No.6 Aluminum Lake, D&C Yellow No.10 Aluminum Lake
112 D&C Red No.27 Aluminum Lake, D&C Red No.30 Aluminum Lake
125 FD&C Blue No.1 Aluminum Lake, FD&C Red No.40 Aluminum Lake, FD&C Yellow No.6 Aluminum Lake
137 FD&C Blue No.1 Aluminum Lake
150 FD&C Blue No.2 Aluminum Lake
175 FD&C Blue No.1 Aluminum Lake, D&C Red No.30 Aluminum Lake, D&C Red No.27 Aluminum Lake
200 FD&C Red No.40 Aluminum Lake
300 FD&C Yellow No.6 Aluminum Lake, FD&C Blue No.1 Aluminum Lake, D&C Yellow No.10 Aluminum Lake

What are the possible side effects of levothyroxine (Levothroid, Levoxyl, Synthroid, Tirosint, Unithroid)?

Stop using levothyroxine and get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

  • headache;
  • sleep problems (insomnia);
  • nervous or irritable feeling;
  • fever, hot flashes, sweating;
  • changes in your menstrual periods;
  • appetite changes, weight changes;

Less serious side effects may include mild hair...

Read All Potential Side Effects and See Pictures of Levothroid »

What are the precautions when taking levothyroxine sodium (Levothroid)?

Before taking levothyroxine, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: increased thyroid hormones (thyrotoxicosis), decreased adrenal gland function, heart disease (such as coronary artery disease, irregular heartbeat), high blood pressure, diabetes.

Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

Current information shows that this drug may be used during pregnancy....

Read All Potential Precautions of Levothroid »

Last reviewed on RxList: 8/17/2007
This monograph has been modified to include the generic and brand name in many instances.

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Levothroid - User Reviews

Levothroid User Reviews

Now you can gain knowledge and insight about a drug treatment with Patient Discussions.

Here is a collection of user reviews for the medication Levothroid sorted by most helpful. Patient Discussions FAQs

Report Problems to the Food and Drug Administration

 

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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