All of the following adverse reactions have been reported with hyoscyamine sulfate. Adverse reactions may include dryness of the mouth; urinary hesitancy and retention; blurred vision; tachycardia; palpitations; mydriasis; increased ocular tension; loss of taste; headache; nervousness; drowsiness; weakness; fatigue; dizziness; insomnia; nausea; vomiting; impotence; constipation; bloated feeling; abdominal pain; diarrhea; allergic reactions or drug idiosyncrasies; urticaria and other dermal manifestations; ataxia; speech disturbance; some degree of mental confusion and/or excitement (especially in elderly persons); short-term memory loss; hallucinations; and decreased sweating.

Read the Levsin SL (hyoscyamine sulfate tablets) Side Effects Center for a complete guide to possible side effects »

Additive adverse effects resulting from cholinergic blockade may occur when Levsin®/SL (hyoscyamine sulfate tablets) is administered concomitantly with other antimuscarinics, amantadine, haloperidol, phenothiazines, monoamine oxidase (MAO) inhibitors, tricyclic antidepressants or some antihistamines.

Antacids may interfere with the absorption of Levsin®/SL (hyoscyamine sulfate tablets) . Administer Levsin®/SL (hyoscyamine sulfate tablets) before meals; antacids after meals.

Last reviewed on RxList: 3/13/2009
This monograph has been modified to include the generic and brand name in many instances.