Lexiscan (Regadenoson Injection) Drug Information: Description, User Reviews, Drug Side Effects, Interactions

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February 10, 2012

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Lexiscan

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Lexiscan®
(regadenoson)

DRUG DESCRIPTION

Regadenoson is an A_2A adenosine receptor agonist that is a coronary vasodilator [see CLINICAL PHARMACOLOGY]. Regadenoson is chemically described as adenosine, 2-[4-[(methylamino)carbonyl]-1H-pyrazol-1-yl]-, monohydrate. Its structural formula is:

Lexiscan® (regadenoson) Structural Formula Illustration

The molecular formula for regadenoson is C₁₅H₁₈N₈O₅•H₂O and its molecular weight is 408.37. Lexiscan is a sterile, nonpyrogenic solution for intravenous injection. The solution is clear and colorless. Each 1 mL in the 5-mL vial or pre-filled syringe contains 0.084 mg of regadenoson monohydrate, corresponding to 0.08 mg regadenoson on an anhydrous basis, 10.9 mg dibasic sodium phosphate dihydrate or 8.7 mg dibasic sodium phosphate anhydrous, 5.4 mg monobasic sodium phosphate monohydrate, 150 mg propylene glycol, 1 mg edetate disodium dihydrate, and Water for Injection, with pH between 6.3 and 7.7.

What are the possible side effects of regadenoson (Lexiscan)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Tell your caregivers at once if you have a serious side effect such as:

chest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, general ill feeling;
slow heart rate, weak pulse, fainting, slow breathing (breathing may stop);
wheezing, trouble breathing; or
feeling like you might pass...

Read All Potential Side Effects and See Pictures of Lexiscan »

Last reviewed on RxList: 10/7/2011
This monograph has been modified to include the generic and brand name in many instances.