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Regadenoson is an A 2A adenosine receptor agonist that is a coronary vasodilator [see CLINICAL PHARMACOLOGY]. Regadenoson is chemically described as adenosine, 2-[4[(methylamino)carbonyl]-1H-pyrazol-1-yl]-, monohydrate. Its structural formula is:
The molecular formula for regadenoson is C15H18N8O5•H2O and its molecular weight is 408.37. Lexiscan is a sterile, nonpyrogenic solution for intravenous injection. The solution is clear and colorless. Each 1 mL in the 5 mL pre-filled syringe contains 0.084 mg of regadenoson monohydrate, corresponding to 0.08 mg regadenoson on an anhydrous basis, 10.9 mg dibasic sodium phosphate dihydrate or 8.7 mg dibasic sodium phosphate anhydrous, 5.4 mg monobasic sodium phosphate monohydrate, 150 mg propylene glycol, 1 mg edetate disodium dihydrate, and Water for Injection, with pH between 6.3 and 7.7.
What are the possible side effects of regadenoson (Lexiscan)?
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Tell your caregivers at once if you have a serious side effect such as:
- chest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, general ill feeling;
- slow heart rate, weak pulse, fainting, slow breathing (breathing may stop);
- dangerously high blood pressure (severe headache, blurred vision, buzzing in your ears, anxiety, confusion, shortness of breath, uneven heart...
Last reviewed on RxList: 10/3/2014
This monograph has been modified to include the generic and brand name in many instances.
Additional Lexiscan Information
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