home > drugs a-z list > lexiscan (regadenoson injection) drug center > lexiscan (regadenoson injection) drug - overdosage and contraindications

Lexiscan overdosage may result in serious reactions [see WARNINGS AND PRECAUTIONS]. In a study of healthy volunteers, symptoms of flushing, dizziness and increased heart rate were assessed as intolerable at Lexiscan doses greater than 0.02 mg/kg.

Aminophylline to Reverse

Effects Aminophylline may be administered in doses ranging from 50 mg to 250 mg by slow intravenous injection (50 mg to 100 mg over 30–60 seconds) to attenuate severe and/or persistent adverse reactions to Lexiscan.

Do not administer Lexiscan to patients with:

• Second- or third- degree AV block, or
• sinus node dysfunction

unless these patients have a functioning artificial pacemaker [see WARNINGS AND PRECAUTIONS].

Last reviewed on RxList: 10/7/2011
This monograph has been modified to include the generic and brand name in many instances.