May 27, 2016
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Lexiscan Patient Information Including Side Effects

Brand Names: Lexiscan

Generic Name: regadenoson (Pronunciation: re ga DEN oh son)

What is regadenoson (Lexiscan)?

Regadenoson is a stress agent that works by increasing blood flow in the arteries of the heart.

Regadenoson is given in preparation for a radiologic (x-ray) examination of blood flow through the heart to test for coronary artery disease.

Regadenoson may also be used for other purposes not listed in this medication guide.

What are the possible side effects of regadenoson (Lexiscan)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Tell your caregivers at once if you have a serious side effect such as:

  • chest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, general ill feeling;
  • slow heart rate, weak pulse, fainting, slow breathing (breathing may stop);
  • dangerously high blood pressure (severe headache, blurred vision, buzzing in your ears, anxiety, confusion, shortness of breath, uneven heart rate);
  • seizure (convulsions);
  • wheezing, trouble breathing; or
  • feeling like you might pass out.

Less serious side effects may include:

  • headache;
  • dizziness;
  • nausea, stomach discomfort, decreased sense of taste;
  • mild chest discomfort; or
  • warmth, redness, or tingly feeling under your skin.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1 800 FDA 1088.

Read the Lexiscan (regadenoson injection) Side Effects Center for a complete guide to possible side effects

What is the most important information I should know about regadenoson (Lexiscan)?

You should not use this medication if you are allergic to regadenoson, or if you have a serious heart condition such as AV block or "sick sinus syndrome" (unless you have a pacemaker).

Before you receive regadenoson, tell your doctor if you have asthma or COPD, a history of heart disease or high blood pressure, or if you have had an illness causing vomiting or diarrhea.

Avoid drinking coffee or other beverages with caffeine for at least 12 hours before your stress test.

Tell your caregivers if you have a serious side effect such as chest pain or heavy feeling, pain spreading to the arm or shoulder, sweating, general ill feeling, wheezing or trouble breathing, slow heart rate, severe headache, seizure (convulsions), weak pulse, slow breathing, or fainting.

Side Effects Centers

Additional Lexiscan Information

Report Problems to the Food and Drug Administration


You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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