In this Article

• What is fosamprenavir (Lexiva)?
• What are the possible side effects of fosamprenavir (Lexiva)?
• What is the most important information I should know about fosamprenavir (Lexiva)?
• What should I discuss with my healthcare provider before taking fosamprenavir (Lexiva)?
• How should I take fosamprenavir (Lexiva)?
• What happens if I miss a dose (Lexiva)?
• What happens if I overdose (Lexiva)?
• What should I avoid while taking fosamprenavir (Lexiva)?
• What other drugs will affect fosamprenavir (Lexiva)?
• Where can I get more information?

What happens if I miss a dose (Lexiva)?

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose (Lexiva)?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking fosamprenavir (Lexiva)?

Taking this medication will not prevent you from passing HIV to other people. Avoid having unprotected sex or sharing razors or toothbrushes. Talk with your doctor about safe ways to prevent HIV transmission during sex. Sharing drug or medicine needles is never safe, even for a healthy person.

What other drugs will affect fosamprenavir (Lexiva)?

• itraconazole (Sporanox) or ketoconazole (Nizoral);
• heart rhythm medicine such as amiodarone (Cordarone, Pacerone), lidocaine, or quinidine (Quin-G);
• an antidepressant such as amitriptyline (Elavil, Vanatrip, Limbitrol), imipramine (Janimine, Tofranil), or paroxetine (Paxil);
• rifampin (Rifadin, Rimactane, Rifater);
• steroid medicine such as dexamethasone (Cortastat, Dexasone, Solurex, DexPak) or fluticasone (Advair, Flonase, Flovent);
• St. John's wort;
• a blood thinner such as warfarin (Coumadin, Jantoven);
• heart or blood pressure medicine such as amlodipine (Norvasc, Caduet, Exforge, Lotrel, Tekamlo, Tribenzor, Twynsta, Amturnide), diltiazem (Cartia, Cardizem), nifedipine (Nifedical, Procardia), verapamil (Calan, Covera, Isoptin, Verelan), and others;
• cholesterol-lowering medicine such as atorvastatin (Lipitor, Caduet), lovastatin (Mevacor, Altoprev, Advicor), simvastatin (Zocor, Simcor, Vytorin);
• drugs that weaken the immune system, such as cyclosporine (Gengraf, Neoral, Sandimmune), sirolimus (Rapamune), or tacrolimus (Prograf);
• other HIV /AIDS medicine such as delavirdine (Rescriptor), efavirenz (Sustiva, Atripla), nevirapine (Viramune), lopinavir/ritonavir (Kaletra), or raltegravir (Isentress);
• insulin or diabetes medication you take by mouth;
• medicines to treat erectile dysfunction, such as sildenafil (Viagra), tadalafil (Cialis), or vardenafil (Levitra);
• seizure medications such as carbamazepine (Carbatrol, Equetro, Tegretol), phenobarbital (Luminal, Solfoton), or phenytoin (Dilantin); or
• stomach acid reducers such as cimetidine (Tagamet), famotidine (Pepcid), nizatidine (Axid), or ranitidine (Zantac).

Where can I get more information?

Your pharmacist can provide more information about fosamprenavir.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

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