In this Article

• What is enalapril and felodipine (Lexxel)?
• What are the possible side effects of enalapril and felodipine (Lexxel)?
• What is the most important information I should know about enalapril and felodipine (Lexxel)?
• What should I discuss with my healthcare provider before taking enalapril and felodipine (Lexxel)?
• How should I take enalapril and felodipine (Lexxel)?
• What happens if I miss a dose (Lexxel)?
• What happens if I overdose (Lexxel)?
• What should I avoid while taking enalapril and felodipine (Lexxel)?
• What other drugs will affect enalapril and felodipine (Lexxel)?
• Where can I get more information?

What should I discuss with my healthcare provider before taking enalapril and felodipine (Lexxel)?

Do not use this medication if you are allergic to enalapril and felodipine or to any other ACE inhibitor, such as benazepril (Lotensin), captopril (Capoten), fosinopril (Monopril), lisinopril (Prinivil, Zestril), moexipril (Univasc), perindopril (Aceon), quinapril (Accupril), ramipril (Altace), or trandolapril (Mavik).

Before using enalapril and felodipine, tell your doctor if you are allergic to any drugs, or if you have:

• kidney disease (or if you are on dialysis);
• liver disease;
• heart disease or congestive heart failure;
• low sodium levels in your body (hyponatremia);
• diabetes; or
• a history of stroke or heart attack.

If you have any of these conditions, you may need a dose adjustment or special tests to safely take this medication.

FDA pregnancy category D. Do not use this medication without telling your doctor if you are pregnant or planning a pregnancy. Enalapril and felodipine could cause birth defects in the baby if you take the medication during pregnancy. Use an effective form of birth control. Stop using this medication and tell your doctor right away if you become pregnant during treatment.

Enalapril and felodipine can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

How should I take enalapril and felodipine (Lexxel)?

Take this medication exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label.

Your doctor may occasionally change your dose to make sure you get the best results from this medication.

Enalapril and felodipine should be taken without food or with a light meal.

Do not crush, chew, or break the extended-release tablet. Swallow the pill whole. Breaking or crushing the pill may cause too much of the drug to be released at one time.

Vomiting, diarrhea, or heavy sweating can cause you to become dehydrated. This can lead to very low blood pressure, electrolyte disorders, or kidney failure while you are taking enalapril and felodipine. Drink plenty of water each while you are taking this medication.

To be sure this medication is helping your condition, your blood pressure will need to be checked on a regular basis. Your kidney function may also need to be tested. Do not miss any scheduled visits to your doctor.

If you need to have any type of surgery, tell the surgeon ahead of time that you are taking enalapril and felodipine. You may need to stop using the medicine for a short time.

Keep using this medicine as directed, even if you feel well. High blood pressure often has no symptoms, so you may not know when your blood pressure is high. You may need to use blood pressure medication for the rest of your life.

Store enalapril and felodipine at room temperature away from moisture, heat, and light.