"What are benzodiazepines, and how do they work?
Benzodiazepines are a class of drugs primarily used for treating anxiety, but they also are effective in treating several other conditions. The exact mechanism of action of benzodiaz"...
Librium Side Effects Center
Medical Editor: John P. Cunha, DO, FACOEP
Librium (chlordiazepoxide) is used to treat anxiety disorders or alcohol withdrawal. It is a benzodiazepine. This medication is available in generic form. Common side effects include drowsiness, dizziness, nausea, constipation, blurred vision, or headache.
The dose of Librium varies depending on the condition being treated. For mild to moderate anxiety, 5 mg or 10 mg, 3 or 4 times daily. For severe anxiety, 20 mg or 25 mg, 3 or 4 times daily. Consult your doctor for pediatric or geriatric dosing. Librium may interact with barbiturates, blood thinners, MAO inhibitors, medicine to treat psychiatric disorders, narcotics, or antidepressants. Tell your doctor all medications you use. Librium is not recommended for use during pregnancy due to the potential for harm to a fetus. Based on information from related drugs, this drug may pass into breast milk and may have undesirable effects on a nursing infant. Breast-feeding while using this medication is not recommended. Withdrawal symptoms may occur if you suddenly stop taking this medication.
Our Librium (chlordiazepoxide) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What is Patient Information in Detail?
Easy-to-read and understand detailed drug information and pill images for the patient or caregiver from Cerner Multum.
Librium in Detail - Patient Information: Side Effects
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have any of these serious side effects:
- depressed mood, thoughts of suicide or hurting yourself;
- restless muscle movements in your eyes, tongue, jaw, or neck;
- hyperactivity, agitation, hostility;
- hallucinations; or
- jaundice (yellowing of the skin or eyes).
Less serious side effects may include:
- drowsiness, tiredness;
- skin rash;
- nausea, vomiting, constipation; or
- irregular menstrual periods.
This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.
Read the entire detailed patient monograph for Librium (Chlordiazepoxide) »
What is Patient Information Overview?
A concise overview of the drug for the patient or caregiver from First DataBank.
Librium Overview - Patient Information: Side Effects
Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
Tell your doctor immediately if any of these unlikely but serious side effects occur: mental/mood changes, slurred speech, clumsiness, trouble walking, decreased/increased interest in sex, tremor, uncontrollable movements, facial or muscle twitching, trouble urinating, sleep disturbances.
Tell your doctor immediately if any of these highly unlikely but very serious side effects occur: fainting, stomach/abdominal pain, persistent nausea, vomiting, fatigue, yellowing eyes or skin, dark urine, persistent sore throat or fever.
A serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction include: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
In the US -
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
Read the entire patient information overview for Librium (Chlordiazepoxide)»
What is Prescribing information?
The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.
Librium FDA Prescribing Information: Side Effects
The necessity of discontinuing therapy because of undesirable effects has been rare. Drowsiness, ataxia and confusion have been reported in some patients particularly the elderly and debilitated. While these effects can be avoided in almost all instances by proper dosage adjustment, they have occasionally been observed at the lower dosage ranges. In a few instances syncope has been reported.
Other adverse reactions reported during therapy include isolated instances of skin eruptions, edema, minor menstrual irregularities, nausea and constipation, extrapyramidal symptoms, as well as increased and decreased libido. Such side effects have been infrequent, and are generally controlled with reduction of dosage. Changes in EEG patterns (low-voltage fast activity) have been observed in patients during and after Librium (chlordiazepoxide) treatment.
Blood dyscrasias (including agranulocytosis), jaundice and hepatic dysfunction have occasionally been reported during therapy. When Librium (chlordiazepoxide) treatment is protracted, periodic blood counts and liver function tests are advisable.
Withdrawal symptoms, similar in character to those noted with barbiturates and alcohol (convulsions, tremor, abdominal and muscle cramps, vomiting and sweating), have occurred following abrupt discontinuance of chlordiazepoxide. The more severe withdrawal symptoms have usually been limited to those patients who had received excessive doses over an extended period of time. Generally milder withdrawal symptoms (eg, dysphoria and insomnia) have been reported following abrupt discontinuance of benzodiazepines taken continuously at therapeutic levels for several months. Consequently, after extended therapy, abrupt discontinuation should generally be avoided and a gradual dosage tapering schedule followed. Addiction-prone individuals (such as drug addicts or alcoholics) should be under careful surveillance when receiving chlordiazepoxide or , other, psychotropic agents because of the predisposition of such patients to habituation and dependence.
Read the entire FDA prescribing information for Librium (Chlordiazepoxide) »
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Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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