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Lichen Planus

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Lichen planus facts

  • Lichen planus is a chronic recurrent rash of unknown cause with no established cure.
  • Lichen planus generally affects adults and can involve any portion of the body, but it has a predilection for the wrists, ankles, and oral and genital tissues.
  • Lichen planus can be quite itchy.
  • Lichen planus may spontaneously resolve.
  • Lichen planus is managed with a variety of topical and oral medications.

What is lichen planus?

Lichen planus is a chronic recurrent rash that is due to inflammation. The rash is characterized by small, flat-topped, many-sided (polygonal) bumps that can grow together into rough, scaly plaques on the skin. There may also be a rash in the lining (mucous membranes) of the mouth or vagina.

Lichen planus is a very curious and poorly understood skin condition. Its name is descriptive in that to some it resembles a simple plant, a lichen, that grows on rocks and tree bark, while planus is Latin for flat.

What causes lichen planus?

The cause of lichen planus is unknown. In certain locales, patients with extensive lichen planus seem to be more likely to have a hepatitis C virus infection of the liver. However, it is unclear if this virus is the cause of lichen planus in such situations.

Some drugs, such as those containing arsenic, bismuth, or gold, can produce an eruption which appears identical to lichen planus. Exposure to certain chemicals used in the development of color photographs can also produce a similar rash. The long-term use of the drugs quinacrine or quinidine (Quinidine Gluconate, Quinidine Sulfate), which is used for malaria, certain microscopic organisms, and worms, may produce hypertrophic lichen planus of the lower legs and other skin and body-wide (systemic) disturbances. Lichenoid eruptions can occur in graft-versus-host disease in people who have received bone marrow transplants. Tissue examination by a pathologist (biopsy) would be necessary distinguish lichenoid drug eruptions from classical lichen planus, which is not caused by medication. Of course, stopping the offending drug is associated with resolution of the eruption.

Medically Reviewed by a Doctor on 4/16/2014

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Source: MedicineNet.com
http://www.medicinenet.com/lichen_planus/article.htm

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