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LINDANE LOTION, USP 1%
WARNINGS
Lindane Lotion should only be used in patients who cannot tolerate or have failed first-line treatment with safer medications for the treatment of scabies. (See INDICATIONS)
Neurologic Toxicity
Seizures and deaths have been reported following Lindane Lotion use with repeat or prolonged application, but also in rare cases following a single application used according to directions. Lindane Lotion should be used with caution for infants, children, the elderly, and individuals with other skin conditions (e.g., atopic dermatitis, psoriasis) and in those who weigh < 110 lbs (50 kg) as they may be at risk of serious neurotoxicity.
Contraindications
Lindane Lotion is contraindicated in premature infants and individuals with known uncontrolled seizure disorders.
Proper Use
Instruct patients on the proper use of Lindane Lotion, the amount to apply, how long to leave it on, and avoiding retreatment. Inform patients that itching occurs after the successful killing of scabies and is not necessarily an indication for retreatment with Lindane Lotion. (See DOSAGE AND ADMINISTRATION.)
Lindane Lotion, USP 1%, is an ectoparasiticide and ovicide. In addition to the active ingredient, lindane, it contains 2-amino-2-methyl- 1-propanol, carrageenan, cetyl alcohol, cocoa butter, glyceryl monostearate, methylparaben, propylene glycol, propylparaben, purified water, stearic acid and trolamine to form a lotion. The pH range is between 6.5 and 8.5. Lindane is the gamma isomer of 1,2,3,4,5,6- hexachlorocyclohexane having the following structural formula:
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Stop using lindane topical and seek emergency medical attention if you experience an uncommon but serious side effect such as
Other less serious side effects may also occur. Talk to your doctor if you experience
Side effects...
Read All Potential Side Effects and See Pictures of Lindane Lotion »
See also Warning section.
Before using lindane lotion, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: a poorly controlled seizure disorder.
Before using this medication, tell your doctor or pharmacist your medical history, especially of: previous use of lindane in the past few months, other skin conditions (e.g., psoriasis, dermatitis), HIV infection, history of serious head injury, history of seizures, brain tumors, severe liver...
Last reviewed on RxList: 4/22/2008
This monograph has been modified to include the generic and brand name in many instances.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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