There is limited experience with overdose of LINZESS. During the clinical development program of LINZESS, single doses of 2897 mcg were administered to 22 healthy volunteers; the safety profile in these subjects was consistent with that in the overall LINZESS-treated population, with diarrhea being the most commonly reported adverse reaction.


LINZESS is contraindicated in:

Last reviewed on RxList: 7/25/2014
This monograph has been modified to include the generic and brand name in many instances.


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