December 1, 2015
Recommended Topic Related To:

Lioresal Intrathecal

"Nov. 1, 2012 -- Two more drugs made by the New England Compounding Center (NECC) are crawling with various kinds of bacteria, FDA tests reveal.

The NECC is the Massachusetts compounding pharmacy whose drugs are the likely source of th"...

Lioresal Intrathecal

LIORESAL® Intrathecal
(baclofen) Injection 0.05 mg/mL, 0.5 mg/mL and 2 mg/mL

For intrathecal injection and infusion only


Drug Substance

LIORESAL (baclofen) Structural Formula Illustration


Chemical Name: 4-amino-3-(p-chlorophenyl) butyric acid

Molecular Formula: C10H12ClNO2

Molecular Weight: 213.67

Description: White to off-white, odorless or practically odorless crystalline powder.

Solubility: Slightly soluble in water, very slightly soluble in methanol and insoluble in chloroform.

pKa: pKa, 1 = 3.87 (carboxyl group) and pKa, 2 = 9.62 (amino group) in water at 20OC.


The contents of each sterile ampoule are described in the following table.

Dosage mg/mL Total Volume mL Medicinal ingredient Non-medicinal ingredients
Baclofen/mg Sodium chloride/mg Water for injection
0.05 1 0.05 9 up to 1 mL
0.5 20 10 180 up to 20 mL
2 5 10 45 up to 5 mL

Last reviewed on RxList: 1/10/2014
This monograph has been modified to include the generic and brand name in many instances.

Report Problems to the Food and Drug Administration


You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

Chronic Pain/Back Pain

Find tips and advances in treatment.

Health Resources
Use Pill Finder Find it Now See Interactions

Pill Identifier on RxList

  • quick, easy,
    pill identification

Find a Local Pharmacy

  • including 24 hour, pharmacies

Interaction Checker

  • Check potential drug interactions
Search the Medical Dictionary for Health Definitions & Medical Abbreviations