Recommended Topic Related To:

Lioresal Intrathecal

"Young children have died or become seriously ill from accidental exposure to a skin patch containing fentanyl, a powerful pain reliever. As a result of this, the Food and Drug Administration (FDA) is issuing a Drug Safety Communication to warn pa"...

Lioresal Intrathecal

LIORESAL® Intrathecal
(baclofen) Injection 0.05 mg/mL, 0.5 mg/mL and 2 mg/mL

For intrathecal injection and infusion only

DRUG DESCRIPTION

Drug Substance

LIORESAL (baclofen) Structural Formula Illustration

Baclofen

Chemical Name: 4-amino-3-(p-chlorophenyl) butyric acid

Molecular Formula: C10H12ClNO2

Molecular Weight: 213.67

Description: White to off-white, odorless or practically odorless crystalline powder.

Solubility: Slightly soluble in water, very slightly soluble in methanol and insoluble in chloroform.

pKa: pKa, 1 = 3.87 (carboxyl group) and pKa, 2 = 9.62 (amino group) in water at 20OC.

Composition

The contents of each sterile ampoule are described in the following table.

Dosage mg/mL Total Volume mL Medicinal ingredient Non-medicinal ingredients
Baclofen/mg Sodium chloride/mg Water for injection
0.05 1 0.05 9 up to 1 mL
0.5 20 10 180 up to 20 mL
2 5 10 45 up to 5 mL

Last reviewed on RxList: 1/10/2014
This monograph has been modified to include the generic and brand name in many instances.

A A A

Report Problems to the Food and Drug Administration

 

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


Chronic Pain/Back Pain

Find tips and advances in treatment.

Health Resources
advertisement
advertisement
Use Pill Finder Find it Now See Interactions

Pill Identifier on RxList

  • quick, easy,
    pill identification

Find a Local Pharmacy

  • including 24 hour, pharmacies

Interaction Checker

  • Check potential drug interactions
Search the Medical Dictionary for Health Definitions & Medical Abbreviations