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home > drugs a-z list > lipofen (fenofibrate) drug center > lipofen (fenofibrate) drug - overdosage and contraindications
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Lipofen
Cholesterol facts
- High cholesterol is also referred to as hypercholesterolemia (hyper=high + cholesterol + emia = in the blood) or hyperlipidemia
- Cholesterol is a fatty substance that is an important part of the outer lining of cells in the body of animals.
- Cholesterol is also found in the blood circulation of humans.
- Cholesterol in the blood originates from dietary intake and liver production.
- Dietary cholesterol comes primarily from animal sources including meat, poultry, fish, and dairy products.
- Organ meats such as liver, are especially high in cholesterol content.
- LDL (low density lipoprotein) cholesterol is called "bad" cholesterol, because elevated levels of LDL cholesterol are associated with an increased risk of coronary heart disease.
- HDL (high density lipoprotein) cholesterol is called the "good cholesterol" because HDL cholesterol particles pre...
Lipofen
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OVERDOSE
There is no specific treatment for overdose with LIPOFEN. General supportive care of the patient is indicated, including monitoring of vital signs and observation of clinical status, should an overdose occur. If indicated, elimination of unabsorbed drug should be achieved by emesis or gastric lavage. The usual precautions should be observed to maintain the airway. Because fenofibrate is highly bound to plasma proteins, hemodialysis should not be considered.
CONTRAINDICATIONS
LIPOFEN is contraindicated in:
- patients with severe renal impairment, including those receiving dialysis [see CLINICAL PHARMACOLOGY].
- patients with active liver disease, including those with primary biliary cirrhosis and unexplained persistent liver function abnormalities [see WARNINGS AND PRECAUTIONS].
- patients with preexisting gallbladder disease [see WARNINGS AND PRECAUTIONS].
- patients with known hypersensitivity to fenofibrate or fenofibric acid [see WARNINGS AND PRECAUTIONS].
- nursing mothers [see Use In Specific Populations].
Last reviewed on RxList: 11/11/2011
This monograph has been modified to include the generic and brand name in many instances.
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