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Liposyn III 30

"The U.S. Food and Drug Administration announced its preliminary determination that partially hydrogenated oils (PHOs), the primary dietary source of artificial trans fat in processed foods, are not "generally recognized as safe" for use in food. "...

Liposyn III 30

OVERDOSE

In the event of fat overload during therapy, stop the infusion of Liposyn III until visual inspection of the plasma, determination of triglyceride concentrations, or measurement of plasma light-scattering activity by nephelometry indicates the lipid has cleared. Re-evaluate the patient and institute appropriate corrective measures. See WARNINGS and PRECAUTIONS.

CONTRAINDICATIONS

LIPOSYN III 30 (liposyn iii 30 intravenous far emulsion) % PHARMACY BULK PACKAGE IS NOT INTENDED FOR DIRECT INTRAVENOUS ADMINISTRATION. DILUTING LIPOSYN III 30 (liposyn iii 30 intravenous far emulsion) % TO A 10% OR 20% CONCENTRATION WITH AN INTRAVENOUS FLUID SUCH AS NORMAL SALINE OR OTHER DILUENT DOES NOT PRODUCE A DILUTION THAT IS EQUIVALENT IN COMPOSITION TO LIPOSYN III 10% OR 20% I.V. FAT EMULSIONS, AND SUCH A DILUTION SHOULD NOT BE GIVEN BY DIRECT INTRAVENOUS ADMINISTRATION (e.g., THROUGH A Y-CONNECTOR).

The administration of Liposyn III (intravenous fat emulsion) is contraindicated in patients demonstrating disturbances in normal fat metabolism such as pathologic hyperlipemia, lipoid nephrosis or acute pancreatitis if accompanied by hyperlipemia.

Partly used containers must not be stored for later use. Do not use any bottle in which there appears to be an oiling out of the emulsion.

Last reviewed on RxList: 2/2/2009
This monograph has been modified to include the generic and brand name in many instances.

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