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Livalo (pitavastatin) to Lower High Cholesterol

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What is Livalo (pitavastatin)?

Livalo (pitavastatin) is a cholesterol-lowering drug approved by the Food and Drug Administration in August 2009. Livalo is an HMG-CoA reductase inhibitor or "statin."

Other statins include:

Statins reduce cholesterol by reducing the activity of HMG-CoA reductase, an enzyme in the liver that is necessary for the production of cholesterol.

In one study Livalo (pitavastatin), 4 mg daily:

  • reduced total cholesterol by 32%
  • reduced LDL ("bad") cholesterol by 45%,
  • reduced triglycerides by 19%,
  • reduced apolipoprotein B by 35%, and
  • raised HDL ("good") cholesterol by 5%.

The 4 mg dose of Livalo (pitavastatin) is comparable to 20 mg of atorvastatin in reducing cholesterol. However, Livalo increases HDL more than Lipitor (atorvastatin). The 2 mg and 4 mg doses of Livalo are comparable to 20 mg and 40 mg doses of Zocor (simvastatin), respectively.

Medically Reviewed by a Doctor on 9/10/2013



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