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Liver Blood Tests (cont.)

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What medications can cause increased liver enzyme tests (abnormal aminotransferase levels)?

A variety of medications can cause abnormal liver enzymes levels in some individuals.

Examples of some of the common medications with potential liver toxicity include:

Pain relief medications such as:

  • aspirin,
  • acetaminophen (Tylenol),
  • ibuprofen (Advil, Motrin),
  • naproxen (Naprosyn, Naprelan, Anaprox, Aleve),
  • diclofenac (Voltaren, Cataflam, Voltaren-XR), and
  • phenylbutazone (Butazolidine)

Anti-seizure medicationssuch as:

  • phenytoin (Dilantin),
  • valproic acid (Depakote, Depakote ER, Depakene, Depacon),
  • carbamazepine (Tegretol, Tegretol XR, Equertro), and
  • phenobarbital

Antibiotics such as:

  • tetracyclines, (for example, tetracycline [Achromycin])
  • sulfonamides,
  • isoniazid (INH) (Nydrazid, Laniazid)
  • sulfamethoxazole (Gantanol),
  • trimethoprim (Trimpex; Proloprim, Primsol)
  • nitrofurantoin (Macrodantin; Furadantin; Macrobid),
  • fluconazole (Diflucan ) and some other anti-fungals, etc.

Cholesterol lowering drugs such as statins:

  • lovastatin (Mevacor, Altocor),
  • pravastatin (Pravachol),
  • atorvastatin (Lipitor),
  • fluvastatin (Lescol),
  • simvastatin (Zocor),
  • rosuvastatin (Crestor), and
  • niacin

Cardiovascular drugs such as:

  • amiodarone (Cordarone),
  • hydralazine (Apresoline)
  • quinidine (Quinaglute, Quinidex), etc.

Other drugs

  • Antidepressant drugs of the tricyclic type

With drug-induced liver enzyme abnormalities, the enzymes usually normalize weeks to months after stopping the medications.

Medically Reviewed by a Doctor on 2/2/2014

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Source: MedicineNet.com
http://www.medicinenet.com/liver_blood_tests/article.htm

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