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(hydrocortisone butyrate 0.1%) Cream, Ointment, & Solution
For Dermatological Use Only.
LOCOID® (hydrocortisone butyrate) cream, ointment and solution contain the topical corticosteroid hydrocortisone butyrate, a non-fluorinated hydrocortisone ester. It has the chemical name (1 IB)-11,21- dihydroxy-17-[(l-oxobutyl)oxy]-pregn-4-ene-3, 20-dione; the molecular formula: C25H3606; the molecular weight: 432.54; and the CAS registry number: 13609-67-1. Its structural formula is:
LOCOID® (hydrocortisone butyrate) Cream, 0.1%:
Each gram of LOCOID® cream contains 1 mg of hydrocortisone butyrate in a hydrophiSic base consisting of cetostearyl alcohol, ceteth-20, mineral oil, white petrolatum, citric acid, sodium citrate, propylparaben, butylparaben (preservatives) and purified water.
LOCOID® (hydrocortisone butyrate) Ointment 0.1%: Each gram of LOCOID® ointment contains 1 mg of hydrocortisone butyrate in a base consisting of mineral oil and polyethylene.
LOCOID® (hydrocortisone butyrate) Solution 0.1%: Each ml of LOCOID® solution contains 1 mg of hydrocortisone butyrate in a vehicle consisting of isopropyl alcohol (50%), glycerin, povidone, citric acid, sodium citrate and purified water.
What are the possible side effects of hydrocortisone topical?
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop using hydrocortisone topical and call your doctor at once if you have any of these serious side effects:
- blurred vision, or seeing halos around lights;
- uneven heartbeats;
- sleep problems (insomnia);
- weight gain, puffiness in your face; or
- feeling tired.
Less serious side effects may include:
- skin redness, burning, itching, or peeling;
What are the precautions when taking hydrocortisone butyrate (Locoid)?
Before using hydrocortisone butyrate, tell your doctor or pharmacist if you are allergic to it; or to other corticosteroids (e.g., prednisone, triamcinolone); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Before using this medication, tell your doctor or pharmacist your medical history, especially of: poor blood circulation, diabetes, immune system problems.
Do not use if there is an infection or sore in the area to be treated.
Rarely, using corticosteroid medications for a long time or over large areas of skin can make it more difficult for your body to respond to physical stress. Therefore, before having surgery or emergency...
Last reviewed on RxList: 3/20/2008
This monograph has been modified to include the generic and brand name in many instances.
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