Locoid (Hydrocortisone Butyrate) Drug Information: Description, User Reviews, Drug Side Effects, Interactions

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February 10, 2012

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Locoid

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LOCOID®
(hydrocortisone butyrate 0.1%) Cream, Ointment, & Solution

For Dermatological Use Only.

DRUG DESCRIPTION

LOCOID® (hydrocortisone butyrate) cream, ointment and solution contain the topical corticosteroid hydrocortisone butyrate, a non-fluorinated hydrocortisone ester. It has the chemical name (1 IB)-11,21- dihydroxy-17-[(l-oxobutyl)oxy]-pregn-4-ene-3, 20-dione; the molecular formula: C25H3606; the molecular weight: 432.54; and the CAS registry number: 13609-67-1. Its structural formula is:

LOCOID (hydrocortisone butyrate) structural formula illustration

LOCOID® (hydrocortisone butyrate) Cream, 0.1%:

Each gram of LOCOID® cream contains 1 mg of hydrocortisone butyrate in a hydrophiSic base consisting of cetostearyl alcohol, ceteth-20, mineral oil, white petrolatum, citric acid, sodium citrate, propylparaben, butylparaben (preservatives) and purified water.

LOCOID® (hydrocortisone butyrate) Ointment 0.1%: Each gram of LOCOID® ointment contains 1 mg of hydrocortisone butyrate in a base consisting of mineral oil and polyethylene.

LOCOID® (hydrocortisone butyrate) Solution 0.1%: Each ml of LOCOID® solution contains 1 mg of hydrocortisone butyrate in a vehicle consisting of isopropyl alcohol (50%), glycerin, povidone, citric acid, sodium citrate and purified water.

What are the precautions when taking hydrocortisone butyrate (Locoid)?

Before using hydrocortisone butyrate, tell your doctor or pharmacist if you are allergic to it; or to other corticosteroids (e.g., prednisone, triamcinolone); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: poor blood circulation, diabetes, immune system problems.

Do not use if there is an infection or sore in the area to be treated.

Rarely, using corticosteroid medications for a long time or over large areas of skin can make it more difficult for your body to respond to physical stress. Therefore, before having surgery or emergency...

Read All Potential Precautions of Locoid »

Last reviewed on RxList: 3/20/2008
This monograph has been modified to include the generic and brand name in many instances.