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LOCOID® (hydrocortisone butyrate) cream, ointment and solution contain the topical corticosteroid hydrocortisone butyrate, a non-fluorinated hydrocortisone ester. It has the chemical name (1 IB)-11,21- dihydroxy-17-[(l-oxobutyl)oxy]-pregn-4-ene-3, 20-dione; the molecular formula: C25H3606; the molecular weight: 432.54; and the CAS registry number: 13609-67-1. Its structural formula is:

LOCOID® (hydrocortisone butyrate) Cream, 0.1%:

Each gram of LOCOID® cream contains 1 mg of hydrocortisone butyrate in a hydrophiSic base consisting of cetostearyl alcohol, ceteth-20, mineral oil, white petrolatum, citric acid, sodium citrate, propylparaben, butylparaben (preservatives) and purified water.

LOCOID® (hydrocortisone butyrate) Ointment 0.1%: Each gram of LOCOID® ointment contains 1 mg of hydrocortisone butyrate in a base consisting of mineral oil and polyethylene.

LOCOID® (hydrocortisone butyrate) Solution 0.1%: Each ml of LOCOID® solution contains 1 mg of hydrocortisone butyrate in a vehicle consisting of isopropyl alcohol (50%), glycerin, povidone, citric acid, sodium citrate and purified water.

Last reviewed on RxList: 3/20/2008
This monograph has been modified to include the generic and brand name in many instances.