Locoid Lipocream (Hydrocortisone Butyrate) Drug Information: Description, User Reviews, Drug Side Effects, Interactions

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May 26, 2012

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Locoid Lipocream User Reviews >>

Locoid Lipocream

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Locoid Lipocream
(hydrocortisone butyrate) Cream, 0.1%

For topical use only

DRUG DESCRIPTION

Locoid Lipocream contains hydrocortisone butyrate, a non-fluorinated hydrocortisone ester [Pregn-4-ene-3, 20-dione, 11, 21-dihydroxy-17- [(1-oxobutyl) oxy (11β)-] for topical dermatologic use.

Chemically, hydrocortisone butyrate is C₂₅H₃₆O₆. It has the following structural formula:

Locoid Lipocream (hydrocortisone butyrate) Structural Formula Illustration

Hydrocortisone butyrate is a white to practically white powder with a molecular weight of 432.56. It is practically insoluble in water, slightly soluble in ether, soluble in methanol, in alcohol, and in acetone, and freely soluble in chloroform.

Each gram of Locoid Lipocream (hydrocortisone butyrate) contains 1 mg hydrocortisone butyrate in a hydrophilic base consisting of cetostearyl alcohol, ceteth-20, mineral oil, white petrolatum, citric acid, sodium citrate, propylparaben and butylparaben (preservatives) and water.

What are the precautions when taking hydrocortisone butyrate (Locoid Lipocream)?

Before using hydrocortisone butyrate, tell your doctor or pharmacist if you are allergic to it; or to other corticosteroids (e.g., prednisone, triamcinolone); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: poor blood circulation, diabetes, immune system problems.

Do not use if there is an infection or sore in the area to be treated.

Rarely, using corticosteroid medications for a long time or over large areas of skin can make it more difficult for your body to respond to physical stress. Therefore, before having surgery or emergency...

Read All Potential Precautions of Locoid Lipocream »

Last reviewed on RxList: 11/6/2009
This monograph has been modified to include the generic and brand name in many instances.