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Locoid Lipocream
(hydrocortisone butyrate) Cream, 0.1%
For topical use only
Locoid Lipocream contains hydrocortisone butyrate, a non-fluorinated hydrocortisone ester [Pregn-4-ene-3, 20-dione, 11, 21-dihydroxy-17- [(1-oxobutyl) oxy (11β)-] for topical dermatologic use.
Chemically, hydrocortisone butyrate is C25H36O6. It has the following structural formula:
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Hydrocortisone butyrate is a white to practically white powder with a molecular weight of 432.56. It is practically insoluble in water, slightly soluble in ether, soluble in methanol, in alcohol, and in acetone, and freely soluble in chloroform.
Each gram of Locoid Lipocream (hydrocortisone butyrate) contains 1 mg hydrocortisone butyrate in a hydrophilic base consisting of cetostearyl alcohol, ceteth-20, mineral oil, white petrolatum, citric acid, sodium citrate, propylparaben and butylparaben (preservatives) and water.
Last reviewed on RxList: 11/6/2009
This monograph has been modified to include the generic and brand name in many instances.
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